Mutant B-Raf Kinase inhibitors, AstraZeneca
TL;DR: Mutant B-Raf Kinase inhibitors, AstraZeneca (CAS 377731-45-8) is a chemical compound with molecular formula C21H27NO5 and molecular weight 373.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-methyl-5-[4-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]butyl]-1,3-dioxane-2-carboxylic acid
Also Known As: Mutant B-Raf Kinase inhibitors, AstraZeneca, J1.844.118G, R-1593, 2-methyl-5-[4-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]butyl]-1,3-dioxane-2-carboxylic Acid, Mutant B-Raf (V600E) kinase inhibitors (cancer), AstraZeneca
| Molecular Formula | C21H27NO5 |
|---|---|
| Molecular Weight | 373.19 g/mol |
| LogP | 4.13504 |
| Topological Polar Surface Area | 81.79 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 373.18893 |
| Heavy Atoms | 27 |
| Complexity | 772.3697 |
Chemical Identifiers
| CAS Number | 377731-45-8 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC(=C(O2)C)CCCCC3COC(OC3)(C)C(=O)O |
Product Overview
Mutant B-Raf Kinase inhibitors, AstraZeneca (CAS 377731-45-8), with molecular formula C21H27NO5 and molecular weight 373.19 g/mol. IUPAC: 2-methyl-5-[4-[5-methyl-2-(4-methylphenyl)-1,3-oxazol-4-yl]butyl]-1,3-dioxane-2-carboxylic acid.
Chemical Property Profile of Mutant B-Raf Kinase inhibitors, AstraZeneca
Property Insights of Mutant B-Raf Kinase inhibitors, AstraZeneca
The XLogP value of 4.13504 indicates that Mutant B-Raf Kinase inhibitors, AstraZeneca is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.79 Ų falls within the moderate polarity range, balancing permeability and solubility for Mutant B-Raf Kinase inhibitors, AstraZeneca. Following Lipinski's Rule of Five, Mutant B-Raf Kinase inhibitors, AstraZeneca has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Mutant B-Raf Kinase inhibitors, AstraZeneca?
The CAS number of Mutant B-Raf Kinase inhibitors, AstraZeneca is 377731-45-8.
What is the molecular formula of Mutant B-Raf Kinase inhibitors, AstraZeneca?
The molecular formula of Mutant B-Raf Kinase inhibitors, AstraZeneca is C21H27NO5.
What is the molecular weight of Mutant B-Raf Kinase inhibitors, AstraZeneca?
The molecular weight of Mutant B-Raf Kinase inhibitors, AstraZeneca is 373.19 g/mol.
Where can I buy Mutant B-Raf Kinase inhibitors, AstraZeneca?
You can request a quote for Mutant B-Raf Kinase inhibitors, AstraZeneca directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Mutant B-Raf Kinase inhibitors, AstraZeneca?
Yes, KEHONG BIO provides custom synthesis services for Mutant B-Raf Kinase inhibitors, AstraZeneca and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.