SCH 412348
TL;DR: SCH 412348 (CAS 377727-26-9) is a chemical compound with molecular formula C22H21F2N9O and molecular weight 465.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-[2-[4-(2,4-difluorophenyl)piperazin-1-yl]ethyl]-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
Also Known As: SCH 412348, HY-U00189, SID:134223332, (7-(2-(4-difluorophenyl)-1-piperazinyl)ethyl)-2-(2-furanyl)-7H-pyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-amine, 10-[2-[4-(2,4-Difluorophenyl)piperazin-1-yl]ethyl]-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
| Molecular Formula | C22H21F2N9O |
|---|---|
| Molecular Weight | 465.18 g/mol |
| LogP | 2.4166 |
| Topological Polar Surface Area | 106.54 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 465.18372 |
| Heavy Atoms | 34 |
| Complexity | 1469.1266 |
Chemical Identifiers
| CAS Number | 377727-26-9 |
|---|---|
| SMILES | C1CN(CCN1CCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5)C6=C(C=C(C=C6)F)F |
Product Overview
SCH 412348 (CAS 377727-26-9), with molecular formula C22H21F2N9O and molecular weight 465.18 g/mol. IUPAC: 10-[2-[4-(2,4-difluorophenyl)piperazin-1-yl]ethyl]-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine.
Chemical Property Profile of SCH 412348
Property Insights of SCH 412348
The XLogP value of 2.4166 suggests moderate lipophilicity, balancing water solubility and membrane permeability for SCH 412348. The TPSA of 106.54 Ų falls within the moderate polarity range, balancing permeability and solubility for SCH 412348. Following Lipinski's Rule of Five, SCH 412348 has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SCH 412348?
The CAS number of SCH 412348 is 377727-26-9.
What is the molecular formula of SCH 412348?
The molecular formula of SCH 412348 is C22H21F2N9O.
What is the molecular weight of SCH 412348?
The molecular weight of SCH 412348 is 465.18 g/mol.
Where can I buy SCH 412348?
You can request a quote for SCH 412348 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SCH 412348?
Yes, KEHONG BIO provides custom synthesis services for SCH 412348 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.