Loperamide hydrochloride specified impurity D
TL;DR: Loperamide hydrochloride specified impurity D (CAS 37743-41-2) is a chemical compound with molecular formula C29H34N2O2 and molecular weight 442.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide
Also Known As: Loperamide EP Impurity D, Loperamide Impurity D, TimTec1_001769, 4-(4-hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide, Loperamide hydrochloride specified impurity D [EP]
| Molecular Formula | C29H34N2O2 |
|---|---|
| Molecular Weight | 442.26 g/mol |
| LogP | 4.4346 |
| Topological Polar Surface Area | 43.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 442.26202 |
| Heavy Atoms | 33 |
| Complexity | 987.4915 |
Chemical Identifiers
| CAS Number | 37743-41-2 |
|---|---|
| SMILES | CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=CC=C2)O)(C3=CC=CC=C3)C4=CC=CC=C4 |
Product Overview
Loperamide hydrochloride specified impurity D (CAS 37743-41-2), with molecular formula C29H34N2O2 and molecular weight 442.26 g/mol. IUPAC: 4-(4-hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide.
Chemical Property Profile of Loperamide hydrochloride specified impurity D
Property Insights of Loperamide hydrochloride specified impurity D
The XLogP value of 4.4346 indicates that Loperamide hydrochloride specified impurity D is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.78 Ų, Loperamide hydrochloride specified impurity D exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Loperamide hydrochloride specified impurity D has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Loperamide hydrochloride specified impurity D?
The CAS number of Loperamide hydrochloride specified impurity D is 37743-41-2.
What is the molecular formula of Loperamide hydrochloride specified impurity D?
The molecular formula of Loperamide hydrochloride specified impurity D is C29H34N2O2.
What is the molecular weight of Loperamide hydrochloride specified impurity D?
The molecular weight of Loperamide hydrochloride specified impurity D is 442.26 g/mol.
Where can I buy Loperamide hydrochloride specified impurity D?
You can request a quote for Loperamide hydrochloride specified impurity D directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Loperamide hydrochloride specified impurity D?
Yes, KEHONG BIO provides custom synthesis services for Loperamide hydrochloride specified impurity D and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.