(Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one
TL;DR: (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one (CAS 377065-99-1) is a chemical compound with molecular formula C20H11Cl2F2N3O2 and molecular weight 433.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4Z)-2-(2-chloro-4,5-difluorophenyl)-4-[(5-chloro-3-methyl-1-phenylpyrazol-4-yl)methylidene]-1,3-oxazol-5-one
Also Known As: (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one, (4Z)-2-(2-chloro-4,5-difluorophenyl)-4-[(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylidene]-1,3-oxazol-5(4H)-one, (4Z)-2-(2-chloro-4,5-difluorophenyl)-4-[(5-chloro-3-methyl-1-phenylpyrazol-4-yl)methylidene]-1,3-oxazol-5-one
| Molecular Formula | C20H11Cl2F2N3O2 |
|---|---|
| Molecular Weight | 433.02 g/mol |
| LogP | 5.11022 |
| Topological Polar Surface Area | 56.48 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 433.01965 |
| Heavy Atoms | 29 |
| Complexity | 1204.1805 |
Chemical Identifiers
| CAS Number | 377065-99-1 |
|---|---|
| SMILES | CC1=NN(C(=C1/C=C\2/C(=O)OC(=N2)C3=CC(=C(C=C3Cl)F)F)Cl)C4=CC=CC=C4 |
Product Overview
(Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one (CAS 377065-99-1), with molecular formula C20H11Cl2F2N3O2 and molecular weight 433.02 g/mol. IUPAC: (4Z)-2-(2-chloro-4,5-difluorophenyl)-4-[(5-chloro-3-methyl-1-phenylpyrazol-4-yl)methylidene]-1,3-oxazol-5-one.
Chemical Property Profile of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one
Property Insights of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one
The XLogP value of 5.11022 indicates that (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.48 Ų, (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one?
The CAS number of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one is 377065-99-1.
What is the molecular formula of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one?
The molecular formula of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one is C20H11Cl2F2N3O2.
What is the molecular weight of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one?
The molecular weight of (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one is 433.02 g/mol.
Where can I buy (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one?
You can request a quote for (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-4-((5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-2-(2-chloro-4,5-difluorophenyl)oxazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.