![6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline structure](/static/products/3770/377064-87-4.webp)
6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline
TL;DR: 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline (CAS 377064-87-4) is a chemical compound with molecular formula C25H20ClN3OS and molecular weight 445.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(6-chloro-4-phenylquinazolin-2-yl)sulfanyl-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone
Also Known As: 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline, 2-((6-chloro-4-phenylquinazolin-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone, 2-(6-chloro-4-phenyl-quinazolin-2-yl)sulfanyl-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone, 2-(6-chloro-4-phenylquinazolin-2-yl)sulfanyl-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone, 2-[(6-chloro-4-phenylquinazolin-2-yl)sulfanyl]-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone
| Molecular Formula | C25H20ClN3OS |
|---|---|
| Molecular Weight | 445.10 g/mol |
| LogP | 6.0217 |
| Topological Polar Surface Area | 46.09 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 445.10156 |
| Heavy Atoms | 31 |
| Complexity | 1262.3444 |
Chemical Identifiers
| CAS Number | 377064-87-4 |
|---|---|
| SMILES | C1CC2=CC=CC=C2N(C1)C(=O)CSC3=NC4=C(C=C(C=C4)Cl)C(=N3)C5=CC=CC=C5 |
Product Overview
6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline (CAS 377064-87-4), with molecular formula C25H20ClN3OS and molecular weight 445.10 g/mol. IUPAC: 2-(6-chloro-4-phenylquinazolin-2-yl)sulfanyl-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone.
Chemical Property Profile of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline
Property Insights of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline
The XLogP value of 6.0217 indicates that 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.09 Ų, 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline?
The CAS number of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline is 377064-87-4.
What is the molecular formula of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline?
The molecular formula of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline is C25H20ClN3OS.
What is the molecular weight of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline?
The molecular weight of 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline is 445.10 g/mol.
Where can I buy 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline?
You can request a quote for 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline?
Yes, KEHONG BIO provides custom synthesis services for 6-chloro-2-{[2-(3,4-dihydroquinolin-1(2H)-yl)-2-oxoethyl]thio}-4-phenylquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.