F0887-0177
TL;DR: F0887-0177 (CAS 377060-40-7) is a chemical compound with molecular formula C21H19FN6O3 and molecular weight 422.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-[(4-fluorophenyl)methyl]-8-[2-[(4-hydroxyphenyl)methylidene]hydrazinyl]-1,3-dimethylpurine-2,6-dione
Also Known As: F0887-0177, 7-(4-fluorobenzyl)-8-(2-(4-hydroxybenzylidene)hydrazinyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione, 7-[(4-fluorophenyl)methyl]-8-[2-[(4-hydroxyphenyl)methylidene]hydrazinyl]-1,3-dimethylpurine-2,6-dione, 7-[(p-fluorophenyl)methyl]-8-{2-[(p-hydroxyphenyl)methylene]hydrazino}-1,3-dimethyl-3,7-dihydro-2H-purine-2,6(1H)-dione
| Molecular Formula | C21H19FN6O3 |
|---|---|
| Molecular Weight | 422.15 g/mol |
| LogP | 1.7727 |
| Topological Polar Surface Area | 106.44 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 422.15027 |
| Heavy Atoms | 31 |
| Complexity | 1399.0623 |
Chemical Identifiers
| CAS Number | 377060-40-7 |
|---|---|
| SMILES | CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)NN=CC3=CC=C(C=C3)O)CC4=CC=C(C=C4)F |
Product Overview
F0887-0177 (CAS 377060-40-7), with molecular formula C21H19FN6O3 and molecular weight 422.15 g/mol. IUPAC: 7-[(4-fluorophenyl)methyl]-8-[2-[(4-hydroxyphenyl)methylidene]hydrazinyl]-1,3-dimethylpurine-2,6-dione.
Chemical Property Profile of F0887-0177
Property Insights of F0887-0177
The XLogP value of 1.7727 suggests moderate lipophilicity, balancing water solubility and membrane permeability for F0887-0177. The TPSA of 106.44 Ų falls within the moderate polarity range, balancing permeability and solubility for F0887-0177. Following Lipinski's Rule of Five, F0887-0177 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F0887-0177?
The CAS number of F0887-0177 is 377060-40-7.
What is the molecular formula of F0887-0177?
The molecular formula of F0887-0177 is C21H19FN6O3.
What is the molecular weight of F0887-0177?
The molecular weight of F0887-0177 is 422.15 g/mol.
Where can I buy F0887-0177?
You can request a quote for F0887-0177 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F0887-0177?
Yes, KEHONG BIO provides custom synthesis services for F0887-0177 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.