(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
TL;DR: (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid (CAS 376608-71-8) is a chemical compound with molecular formula C10H8F2O2 and molecular weight 198.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
Also Known As: (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid, Ticagrelor Impurity 8, Ticagrelor Impurity 19, Ticagrelor Impurity 74, Ticagrelor Related Compound 28
| Molecular Formula | C10H8F2O2 |
|---|---|
| Molecular Weight | 198.05 g/mol |
| LogP | 2.1529 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 198.04924 |
| Heavy Atoms | 14 |
| Complexity | 389.70844 |
Chemical Identifiers
| CAS Number | 376608-71-8 |
|---|---|
| SMILES | C1[C@H]([C@@H]1C(=O)O)C2=CC(=C(C=C2)F)F |
Product Overview
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid (CAS 376608-71-8), with molecular formula C10H8F2O2 and molecular weight 198.05 g/mol. IUPAC: trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid.
Chemical Property Profile of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
Property Insights of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
The XLogP value of 2.1529 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid. With a topological polar surface area (TPSA) of 37.3 Ų, (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid?
The CAS number of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid is 376608-71-8.
What is the molecular formula of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid?
The molecular formula of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid is C10H8F2O2.
What is the molecular weight of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid?
The molecular weight of (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid is 198.05 g/mol.
Where can I buy (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid?
You can request a quote for (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.