![8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one structure](/static/products/3763/376373-87-4.webp)
8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one
TL;DR: 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one (CAS 376373-87-4) is a chemical compound with molecular formula C18H14FN3O2 and molecular weight 323.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-fluoro-3-[(2-methoxyphenyl)methyl]-5H-pyrimido[5,4-b]indol-4-one
Also Known As: F3382-3124, VU0614603-1, 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one, 8-fluoro-3-[(2-methoxyphenyl)methyl]-3H,4H,5H-pyrimido[5,4-b]indol-4-one, 8-fluoro-3-[(2-methoxyphenyl)methyl]-5H-pyrimido[5,4-b]indol-4-one
| Molecular Formula | C18H14FN3O2 |
|---|---|
| Molecular Weight | 323.11 g/mol |
| LogP | 3.0738 |
| Topological Polar Surface Area | 59.91 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 323.107 |
| Heavy Atoms | 24 |
| Complexity | 1114.3516 |
Chemical Identifiers
| CAS Number | 376373-87-4 |
|---|---|
| SMILES | COC1=CC=CC=C1CN2C=NC3=C(C2=O)NC4=C3C=C(C=C4)F |
Product Overview
8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one (CAS 376373-87-4), with molecular formula C18H14FN3O2 and molecular weight 323.11 g/mol. IUPAC: 8-fluoro-3-[(2-methoxyphenyl)methyl]-5H-pyrimido[5,4-b]indol-4-one.
Chemical Property Profile of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one
Property Insights of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one
The XLogP value of 3.0738 indicates that 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.91 Ų, 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one?
The CAS number of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one is 376373-87-4.
What is the molecular formula of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one?
The molecular formula of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one is C18H14FN3O2.
What is the molecular weight of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one?
The molecular weight of 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one is 323.11 g/mol.
Where can I buy 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one?
You can request a quote for 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 8-fluoro-3-(2-methoxybenzyl)-3H-pyrimido[5,4-b]indol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.