Pregnane-20-one structure

Pregnane-20-one

TL;DR: Pregnane-20-one (CAS 37624-87-6) is a chemical compound with molecular formula C21H34O and molecular weight 302.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(8R,9S,10S,13S,14S,17S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone

Also Known As: Pregnan-20-one, Pregnane-20-one, 20-oxo-pregnane, A-pregnan-20-one, Pregnan-20-one(7CI,9CI)

CAS: 37624-87-6
Molecular Formula C21H34O
Molecular Weight 302.26 g/mol
LogP 6.6
Topological Polar Surface Area 17.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 302.26096
Heavy Atoms 22
Complexity 469.0

Chemical Identifiers

CAS Number 37624-87-6
SMILES CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CCCC4)C)C
InChIKey RSRDWHPVTMQUGZ-OZIWPBGVSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Catalysts (1 patents) Heterocyclic Building Blocks (57 patents) Organic Building Blocks (1 patents) Pharmaceutical Intermediates (26 patents)

Product Overview

Pregnane-20-one (CAS 37624-87-6), with molecular formula C21H34O and molecular weight 302.26 g/mol. IUPAC: 1-[(8R,9S,10S,13S,14S,17S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pregnane-20-one

XLogP
6.6
TPSA (Topological Polar Surface Area)
17.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
22
Complexity
469.0
Exact Mass
302.26096
Monoisotopic Mass
302.26096
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pregnane-20-one

The XLogP value of 6.6 indicates that Pregnane-20-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.1 Ų, Pregnane-20-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Pregnane-20-one has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pregnane-20-one?

The CAS number of Pregnane-20-one is 37624-87-6.

What is the molecular formula of Pregnane-20-one?

The molecular formula of Pregnane-20-one is C21H34O.

What is the molecular weight of Pregnane-20-one?

The molecular weight of Pregnane-20-one is 302.26 g/mol.

Where can I buy Pregnane-20-one?

You can request a quote for Pregnane-20-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pregnane-20-one?

Yes, KEHONG BIO provides custom synthesis services for Pregnane-20-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?