XIAP antagonist 1 structure

XIAP antagonist 1

TL;DR: XIAP antagonist 1 (CAS 375835-04-4) is a chemical compound with molecular formula C23H25ClN4O3 and molecular weight 440.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl 3-[[2-(4-benzylpiperazin-1-yl)acetyl]amino]-5-chloro-1H-indole-2-carboxylate

Also Known As: XIAP antagonist 1, EX-A11326, Methyl 3-[[2-(4-benzylpiperazin-1-yl)acetyl]amino]-5-chloro-1H-indole-2-carboxylate, methyl 3-(2-(4-benzylpiperazin-1-yl)acetamido)-5-chloro-1H-indole-2-carboxylate, methyl 3-{[(4-benzylpiperazin-1-yl)acetyl]amino}-5-chloro-1H-indole-2-carboxylate

CAS: 375835-04-4
Molecular Formula C23H25ClN4O3
Molecular Weight 440.16 g/mol
LogP 3.3642
Topological Polar Surface Area 77.67 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 440.16153
Heavy Atoms 31
Complexity 1075.12

Chemical Identifiers

CAS Number 375835-04-4
SMILES COC(=O)C1=C(C2=C(N1)C=CC(=C2)Cl)NC(=O)CN3CCN(CC3)CC4=CC=CC=C4

Product Overview

XIAP antagonist 1 (CAS 375835-04-4), with molecular formula C23H25ClN4O3 and molecular weight 440.16 g/mol. IUPAC: methyl 3-[[2-(4-benzylpiperazin-1-yl)acetyl]amino]-5-chloro-1H-indole-2-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of XIAP antagonist 1

XLogP
3.3642
TPSA (Topological Polar Surface Area)
77.67
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
31
Complexity
1075.12
Exact Mass
440.16153
Monoisotopic Mass
440.16153
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of XIAP antagonist 1

The XLogP value of 3.3642 indicates that XIAP antagonist 1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.67 Ų falls within the moderate polarity range, balancing permeability and solubility for XIAP antagonist 1. Following Lipinski's Rule of Five, XIAP antagonist 1 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of XIAP antagonist 1?

The CAS number of XIAP antagonist 1 is 375835-04-4.

What is the molecular formula of XIAP antagonist 1?

The molecular formula of XIAP antagonist 1 is C23H25ClN4O3.

What is the molecular weight of XIAP antagonist 1?

The molecular weight of XIAP antagonist 1 is 440.16 g/mol.

Where can I buy XIAP antagonist 1?

You can request a quote for XIAP antagonist 1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for XIAP antagonist 1?

Yes, KEHONG BIO provides custom synthesis services for XIAP antagonist 1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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