RefChem:183364
TL;DR: RefChem:183364 (CAS 37555-10-5) is a chemical compound with molecular formula C18H15ClN2O and molecular weight 310.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chloro-1-(cyclopropylmethyl)-4-phenylquinazolin-2-one
Also Known As: SL 512, 8-chloro-1-(cyclopropylmethyl)-4-phenylquinazolin-2-one, 1-Cyclopropylmethyl-4-phenyl-8-chloro-2(1H)-quinazolinone, 8-Chloro-1-(cyclopropylmethyl)-4-phenyl-2(1H)-quinazolinone, 8-Chloro-1-(cyclopropylmethyl)-4-phenylquinazolin-2(1H)-one
| Molecular Formula | C18H15ClN2O |
|---|---|
| Molecular Weight | 310.09 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 32.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 3 |
| Exact Mass | 310.08728 |
| Heavy Atoms | 22 |
| Complexity | 468.0 |
Chemical Identifiers
| CAS Number | 37555-10-5 |
|---|---|
| SMILES | C1CC1CN2C3=C(C=CC=C3Cl)C(=NC2=O)C4=CC=CC=C4 |
| InChIKey | WXSDDKIGXBLFRQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
RefChem:183364 (CAS 37555-10-5), with molecular formula C18H15ClN2O and molecular weight 310.09 g/mol. IUPAC: 8-chloro-1-(cyclopropylmethyl)-4-phenylquinazolin-2-one.
Chemical Property Profile of RefChem:183364
Property Insights of RefChem:183364
The XLogP value of 4.2 indicates that RefChem:183364 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.7 Ų, RefChem:183364 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:183364 has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:183364?
The CAS number of RefChem:183364 is 37555-10-5.
What is the molecular formula of RefChem:183364?
The molecular formula of RefChem:183364 is C18H15ClN2O.
What is the molecular weight of RefChem:183364?
The molecular weight of RefChem:183364 is 310.09 g/mol.
Where can I buy RefChem:183364?
You can request a quote for RefChem:183364 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:183364?
Yes, KEHONG BIO provides custom synthesis services for RefChem:183364 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.