![2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione structure](/static/products/3753/375360-85-3.webp)
2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione
TL;DR: 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione (CAS 375360-85-3) is a chemical compound with molecular formula C22H26N4O4S and molecular weight 442.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7,18,18-trimethyl-14-morpholin-4-yl-17-oxa-11-thia-3,8,13-triazapentacyclo[10.8.0.02,10.03,7.015,20]icosa-1(12),2(10),13,15(20)-tetraene-4,9-dione
Also Known As: 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione, 2,2,9a-trimethyl-5-(morpholin-4-yl)-1,4,9,9a,10,11-hexahydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12-dione
| Molecular Formula | C22H26N4O4S |
|---|---|
| Molecular Weight | 442.17 g/mol |
| LogP | 2.5706 |
| Topological Polar Surface Area | 84.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 442.16748 |
| Heavy Atoms | 31 |
| Complexity | 1136.4648 |
Chemical Identifiers
| CAS Number | 375360-85-3 |
|---|---|
| SMILES | CC1(CC2=C(CO1)C(=NC3=C2C4=C(S3)C(=O)NC5(N4C(=O)CC5)C)N6CCOCC6)C |
Product Overview
2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione (CAS 375360-85-3), with molecular formula C22H26N4O4S and molecular weight 442.17 g/mol. IUPAC: 7,18,18-trimethyl-14-morpholin-4-yl-17-oxa-11-thia-3,8,13-triazapentacyclo[10.8.0.02,10.03,7.015,20]icosa-1(12),2(10),13,15(20)-tetraene-4,9-dione.
Chemical Property Profile of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione
Property Insights of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione
The XLogP value of 2.5706 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione. The TPSA of 84.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione. Following Lipinski's Rule of Five, 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione?
The CAS number of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione is 375360-85-3.
What is the molecular formula of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione?
The molecular formula of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione is C22H26N4O4S.
What is the molecular weight of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione?
The molecular weight of 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione is 442.17 g/mol.
Where can I buy 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione?
You can request a quote for 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione?
Yes, KEHONG BIO provides custom synthesis services for 2,2,9a-trimethyl-5-morpholino-9,9a,10,11-tetrahydro-1H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[2,3-e]pyrrolo[1,2-a]pyrimidine-8,12(2H,4H)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.