F1154-0219
TL;DR: F1154-0219 (CAS 375357-47-4) is a chemical compound with molecular formula C20H18N4O4S2 and molecular weight 442.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 5-cyano-4-(2-methylphenyl)-2-oxo-6-[2-oxo-2-(1,3-thiazol-2-ylamino)ethyl]sulfanyl-3,4-dihydro-1H-pyridine-3-carboxylate
Also Known As: F1154-0219, methyl 5-cyano-2-hydroxy-4-(2-methylphenyl)-6-{[2-oxo-2-(1,3-thiazol-2-ylamino)ethyl]sulfanyl}-3,4-dihydropyridine-3-carboxylate, methyl 5-cyano-2-oxo-6-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-4-(o-tolyl)-1,2,3,4-tetrahydropyridine-3-carboxylate, methyl 5-cyano-4-(2-methylphenyl)-2-oxo-6-({[(1,3-thiazol-2-yl)carbamoyl]methyl}sulfanyl)-1,2,3,4-tetrahydropyridine-3-carboxylate, methyl 5-cyano-4-(2-methylphenyl)-2-oxo-6-[2-oxo-2-(1,3-thiazol-2-ylamino)ethyl]sulfanyl-3,4-dihydro-1H-pyridine-3-carboxylate
| Molecular Formula | C20H18N4O4S2 |
|---|---|
| Molecular Weight | 442.08 g/mol |
| LogP | 2.5612 |
| Topological Polar Surface Area | 121.18 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 442.07693 |
| Heavy Atoms | 30 |
| Complexity | 1043.3259 |
Chemical Identifiers
| CAS Number | 375357-47-4 |
|---|---|
| SMILES | CC1=CC=CC=C1C2C(C(=O)NC(=C2C#N)SCC(=O)NC3=NC=CS3)C(=O)OC |
Product Overview
F1154-0219 (CAS 375357-47-4), with molecular formula C20H18N4O4S2 and molecular weight 442.08 g/mol. IUPAC: methyl 5-cyano-4-(2-methylphenyl)-2-oxo-6-[2-oxo-2-(1,3-thiazol-2-ylamino)ethyl]sulfanyl-3,4-dihydro-1H-pyridine-3-carboxylate.
Chemical Property Profile of F1154-0219
Property Insights of F1154-0219
The XLogP value of 2.5612 suggests moderate lipophilicity, balancing water solubility and membrane permeability for F1154-0219. The TPSA of 121.18 Ų falls within the moderate polarity range, balancing permeability and solubility for F1154-0219. Following Lipinski's Rule of Five, F1154-0219 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1154-0219?
The CAS number of F1154-0219 is 375357-47-4.
What is the molecular formula of F1154-0219?
The molecular formula of F1154-0219 is C20H18N4O4S2.
What is the molecular weight of F1154-0219?
The molecular weight of F1154-0219 is 442.08 g/mol.
Where can I buy F1154-0219?
You can request a quote for F1154-0219 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1154-0219?
Yes, KEHONG BIO provides custom synthesis services for F1154-0219 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.