2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one
TL;DR: 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one (CAS 375356-01-7) is a chemical compound with molecular formula C20H13ClN2O2 and molecular weight 348.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one
Also Known As: 2-(2-chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one, 2-(2-chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4(3H)-one
| Molecular Formula | C20H13ClN2O2 |
|---|---|
| Molecular Weight | 348.07 g/mol |
| LogP | 4.4 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 348.06656 |
| Heavy Atoms | 25 |
| Complexity | 538.0 |
Chemical Identifiers
| CAS Number | 375356-01-7 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=O)N(C(=N2)C3=CC=CC=C3Cl)C4=CC=CC=C4O |
| InChIKey | RJWPMZLEPDBFLE-UHFFFAOYSA-N |
Product Overview
2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one (CAS 375356-01-7), with molecular formula C20H13ClN2O2 and molecular weight 348.07 g/mol. IUPAC: 2-(2-chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one.
Chemical Property Profile of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one
Property Insights of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one
The XLogP value of 4.4 indicates that 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.9 Ų, 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one?
The CAS number of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one is 375356-01-7.
What is the molecular formula of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one?
The molecular formula of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one is C20H13ClN2O2.
What is the molecular weight of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one?
The molecular weight of 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one is 348.07 g/mol.
Where can I buy 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one?
You can request a quote for 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(2-Chlorophenyl)-3-(2-hydroxyphenyl)quinazolin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.