Methyl 1-chloroisoquinoline-4-carboxylate structure

Methyl 1-chloroisoquinoline-4-carboxylate

TL;DR: Methyl 1-chloroisoquinoline-4-carboxylate (CAS 37497-86-2) is a chemical compound with molecular formula C11H8ClNO2 and molecular weight 221.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl 1-chloroisoquinoline-4-carboxylate

Also Known As: Methyl 1-chloroisoquinoline-4-carboxylate, methyl 1-chloro-4-isoquinolinecarboxylate, 2-Methylbenzo[b]thiophene, methylchloroisoquinolinecarboxylate, 1-chloro-isoquinoline-4-carboxylic acid methyl ester

CAS: 37497-86-2
Molecular Formula C11H8ClNO2
Molecular Weight 221.02 g/mol
LogP 2.6748
Topological Polar Surface Area 39.19 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 1
Exact Mass 221.02435
Heavy Atoms 15
Complexity 524.97687

Chemical Identifiers

CAS Number 37497-86-2
SMILES COC(=O)C1=CN=C(C2=CC=CC=C21)Cl

Product Overview

Methyl 1-chloroisoquinoline-4-carboxylate (CAS 37497-86-2), with molecular formula C11H8ClNO2 and molecular weight 221.02 g/mol. IUPAC: methyl 1-chloroisoquinoline-4-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Methyl 1-chloroisoquinoline-4-carboxylate

XLogP
2.6748
TPSA (Topological Polar Surface Area)
39.19
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
1
Heavy Atoms
15
Complexity
524.97687
Exact Mass
221.02435
Monoisotopic Mass
221.02435
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Methyl 1-chloroisoquinoline-4-carboxylate

The XLogP value of 2.6748 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Methyl 1-chloroisoquinoline-4-carboxylate. With a topological polar surface area (TPSA) of 39.19 Ų, Methyl 1-chloroisoquinoline-4-carboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Methyl 1-chloroisoquinoline-4-carboxylate has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Methyl 1-chloroisoquinoline-4-carboxylate?

The CAS number of Methyl 1-chloroisoquinoline-4-carboxylate is 37497-86-2.

What is the molecular formula of Methyl 1-chloroisoquinoline-4-carboxylate?

The molecular formula of Methyl 1-chloroisoquinoline-4-carboxylate is C11H8ClNO2.

What is the molecular weight of Methyl 1-chloroisoquinoline-4-carboxylate?

The molecular weight of Methyl 1-chloroisoquinoline-4-carboxylate is 221.02 g/mol.

Where can I buy Methyl 1-chloroisoquinoline-4-carboxylate?

You can request a quote for Methyl 1-chloroisoquinoline-4-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Methyl 1-chloroisoquinoline-4-carboxylate?

Yes, KEHONG BIO provides custom synthesis services for Methyl 1-chloroisoquinoline-4-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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