F1103-0348
TL;DR: F1103-0348 (CAS 374916-47-9) is a chemical compound with molecular formula C18H9BrF3N3O2S and molecular weight 466.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-bromo-3-[4-hydroxy-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]indol-2-one
Also Known As: F1103-0348, (2Z,5Z)-5-(5-bromo-2-oxoindolin-3-ylidene)-2-((3-(trifluoromethyl)phenyl)imino)thiazolidin-4-one, 5-bromo-3-[(2Z,5Z)-4-oxo-2-{[3-(trifluoromethyl)phenyl]imino}-1,3-thiazolidin-5-ylidene]-2,3-dihydro-1H-indol-2-one, 5-(5-bromo-2-oxo-1H-indol-3-ylidene)-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-4-one, 5-bromo-3-[4-hydroxy-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]indol-2-one
| Molecular Formula | C18H9BrF3N3O2S |
|---|---|
| Molecular Weight | 466.96 g/mol |
| LogP | 3.7324 |
| Topological Polar Surface Area | 74.58 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 466.95508 |
| Heavy Atoms | 28 |
| Complexity | 1237.6033 |
Chemical Identifiers
| CAS Number | 374916-47-9 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC2=NC(=C(S2)C3=C4C=C(C=CC4=NC3=O)Br)O)C(F)(F)F |
Product Overview
F1103-0348 (CAS 374916-47-9), with molecular formula C18H9BrF3N3O2S and molecular weight 466.96 g/mol. IUPAC: 5-bromo-3-[4-hydroxy-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]indol-2-one.
Chemical Property Profile of F1103-0348
Property Insights of F1103-0348
The XLogP value of 3.7324 indicates that F1103-0348 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.58 Ų falls within the moderate polarity range, balancing permeability and solubility for F1103-0348. Following Lipinski's Rule of Five, F1103-0348 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1103-0348?
The CAS number of F1103-0348 is 374916-47-9.
What is the molecular formula of F1103-0348?
The molecular formula of F1103-0348 is C18H9BrF3N3O2S.
What is the molecular weight of F1103-0348?
The molecular weight of F1103-0348 is 466.96 g/mol.
Where can I buy F1103-0348?
You can request a quote for F1103-0348 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1103-0348?
Yes, KEHONG BIO provides custom synthesis services for F1103-0348 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.