Colistin nonapeptide
TL;DR: Colistin nonapeptide (CAS 37481-35-9) is a chemical compound with molecular formula C40H76N14O11 and molecular weight 928.58 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-N-[4-amino-1-oxo-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]-3-hydroxybutanamide
Also Known As: Colistin nonapeptide, 6H-Pyrrolo[2,3-g]-1,2-benzisoxazole(9CI), 2-amino-N-[4-amino-1-oxo-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]-3-hydroxybutanamide, Polymyxin E1, 1-de(N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid)-, (S)-, n-(4-amino-1-oxo-1-{[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl)threoninamide
| Molecular Formula | C40H76N14O11 |
|---|---|
| Molecular Weight | 928.58 g/mol |
| LogP | -5.1 |
| Topological Polar Surface Area | 432.0 Ų |
| Hydrogen Bond Donors | 16 |
| Hydrogen Bond Acceptors | 16 |
| Rotatable Bonds | 18 |
| Exact Mass | 928.5818 |
| Heavy Atoms | 65 |
| Complexity | 1610.0 |
Chemical Identifiers
| CAS Number | 37481-35-9 |
|---|---|
| SMILES | CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCCC(C(=O)NC(C(=O)N1)CCN)NC(=O)C(CCN)NC(=O)C(C(C)O)N)C(C)O)CCN)CCN)CC(C)C |
| InChIKey | WNPBEUWOUYCJJR-UHFFFAOYSA-N |
Product Overview
Colistin nonapeptide (CAS 37481-35-9), with molecular formula C40H76N14O11 and molecular weight 928.58 g/mol. IUPAC: 2-amino-N-[4-amino-1-oxo-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]-3-hydroxybutanamide.
Chemical Property Profile of Colistin nonapeptide
Property Insights of Colistin nonapeptide
The XLogP value of -5.1 indicates that Colistin nonapeptide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 432.0 Ų indicates high polarity, suggesting Colistin nonapeptide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Colistin nonapeptide has 16 hydrogen bond donor(s) and 16 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colistin nonapeptide?
The CAS number of Colistin nonapeptide is 37481-35-9.
What is the molecular formula of Colistin nonapeptide?
The molecular formula of Colistin nonapeptide is C40H76N14O11.
What is the molecular weight of Colistin nonapeptide?
The molecular weight of Colistin nonapeptide is 928.58 g/mol.
Where can I buy Colistin nonapeptide?
You can request a quote for Colistin nonapeptide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colistin nonapeptide?
Yes, KEHONG BIO provides custom synthesis services for Colistin nonapeptide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.