RefChem:227844 structure

RefChem:227844

TL;DR: RefChem:227844 (CAS 37480-17-4) is a chemical compound with molecular formula C22H27Cl2NO2 and molecular weight 407.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(5S)-8-chloro-5-phenyl-4-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-1-benzoxepin-5-ol chloride

Also Known As: (cis)-(+-)-2,3,4,5-Tetrahydro-8-chloro-5-phenyl-4-(1-piperidinylmethyl)-1-benzoxepin-5-ol HCl, (cis)-(+-)-4-Piperidinomethyl-5-phenyl-8-chloro-2,3,4,5-tetrahydro-1-benzoxepin-5-ol HCl, 1-Benzoxepin-5-ol, 2,3,4,5-tetrahydro-8-chloro-5-phenyl-4-(1-piperidinylmethyl)-, hydrochloride, cis-(+-)-, 1-BENZOXEPIN-5-OL, 2,3,4,5-TETRAHYDRO-8-CHLORO-5-PHENYL-4-(1-PIPERIDINYLMETHYL)-, (5S)-8-chloro-5-phenyl-4-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-1-benzoxepin-5-ol chloride

CAS: 37480-17-4
Molecular Formula C22H27Cl2NO2
Molecular Weight 407.14 g/mol
LogP 0.05
Topological Polar Surface Area 33.9 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 3
Exact Mass 407.14188
Heavy Atoms 27
Complexity 449.0

Chemical Identifiers

CAS Number 37480-17-4
SMILES C1CC[NH+](CC1)CC2CCOC3=C([C@]2(C4=CC=CC=C4)O)C=CC(=C3)Cl.[Cl-]
InChIKey YKNKWWBOSAFDPV-HDNPKDEKSA-N

Product Overview

RefChem:227844 (CAS 37480-17-4), with molecular formula C22H27Cl2NO2 and molecular weight 407.14 g/mol. IUPAC: (5S)-8-chloro-5-phenyl-4-(piperidin-1-ium-1-ylmethyl)-3,4-dihydro-2H-1-benzoxepin-5-ol chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of RefChem:227844

XLogP
0.05
TPSA (Topological Polar Surface Area)
33.9
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
3
Heavy Atoms
27
Complexity
449.0
Exact Mass
407.14188
Monoisotopic Mass
407.14188
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of RefChem:227844

The XLogP value of 0.05 suggests moderate lipophilicity, balancing water solubility and membrane permeability for RefChem:227844. With a topological polar surface area (TPSA) of 33.9 Ų, RefChem:227844 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:227844 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of RefChem:227844?

The CAS number of RefChem:227844 is 37480-17-4.

What is the molecular formula of RefChem:227844?

The molecular formula of RefChem:227844 is C22H27Cl2NO2.

What is the molecular weight of RefChem:227844?

The molecular weight of RefChem:227844 is 407.14 g/mol.

Where can I buy RefChem:227844?

You can request a quote for RefChem:227844 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for RefChem:227844?

Yes, KEHONG BIO provides custom synthesis services for RefChem:227844 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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