PHA-927F free base
TL;DR: PHA-927F free base (CAS 374670-24-3) is a chemical compound with molecular formula C24H26ClN7O4 and molecular weight 511.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-amino-5-[1-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxoethyl]-3-chloro-6-oxo-5-(propan-2-ylamino)pyrazin-2-yl]benzoic acid
Also Known As: PHA-927F free base, Pyrazinone Analog 34, PHA927, J2.021.274H, 3-Amino-5-(1-((((4-carbamimidoylphenyl)methyl)carbamoyl)methyl)-3-chloro-6-oxo-5-((propan-2-yl)amino)-1,6-dihydropyrazin-2-yl)benzoic acid
| Molecular Formula | C24H26ClN7O4 |
|---|---|
| Molecular Weight | 511.17 g/mol |
| LogP | 2.26487 |
| Topological Polar Surface Area | 189.21 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 511.1735 |
| Heavy Atoms | 36 |
| Complexity | 1384.4478 |
Chemical Identifiers
| CAS Number | 374670-24-3 |
|---|---|
| SMILES | CC(C)NC1=NC(=C(N(C1=O)CC(=O)NCC2=CC=C(C=C2)C(=N)N)C3=CC(=CC(=C3)N)C(=O)O)Cl |
Product Overview
PHA-927F free base (CAS 374670-24-3), with molecular formula C24H26ClN7O4 and molecular weight 511.17 g/mol. IUPAC: 3-amino-5-[1-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxoethyl]-3-chloro-6-oxo-5-(propan-2-ylamino)pyrazin-2-yl]benzoic acid.
Chemical Property Profile of PHA-927F free base
Property Insights of PHA-927F free base
The XLogP value of 2.26487 suggests moderate lipophilicity, balancing water solubility and membrane permeability for PHA-927F free base. The TPSA of 189.21 Ų indicates high polarity, suggesting PHA-927F free base may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, PHA-927F free base has 6 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of PHA-927F free base?
The CAS number of PHA-927F free base is 374670-24-3.
What is the molecular formula of PHA-927F free base?
The molecular formula of PHA-927F free base is C24H26ClN7O4.
What is the molecular weight of PHA-927F free base?
The molecular weight of PHA-927F free base is 511.17 g/mol.
Where can I buy PHA-927F free base?
You can request a quote for PHA-927F free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for PHA-927F free base?
Yes, KEHONG BIO provides custom synthesis services for PHA-927F free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.