2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide
TL;DR: 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide (CAS 374617-57-9) is a chemical compound with molecular formula C25H18F6N2O2 and molecular weight 492.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(4-methylphenyl)methylidene]-N,N'-bis[3-(trifluoromethyl)phenyl]propanediamide
Also Known As: Salor-int l470082-1ea, 2-(4-methylbenzylidene)-N,N'-bis[3-(trifluoromethyl)phenyl]propanediamide, 2-(4-METHYLBENZYLIDENE)-N(1),N(3)-BIS(3-(TRIFLUOROMETHYL)PHENYL)MALONAMIDE, 2-[(4-methylphenyl)methylidene]-N,N'-bis[3-(trifluoromethyl)phenyl]propanediamide, 2-(4-Methylbenzylidene)-N1,N3-bis(3-(trifluoromethyl)phenyl)malonamide
| Molecular Formula | C25H18F6N2O2 |
|---|---|
| Molecular Weight | 492.13 g/mol |
| LogP | 6.69342 |
| Topological Polar Surface Area | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 492.12726 |
| Heavy Atoms | 35 |
| Complexity | 1188.439 |
Chemical Identifiers
| CAS Number | 374617-57-9 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C=C(C(=O)NC2=CC=CC(=C2)C(F)(F)F)C(=O)NC3=CC=CC(=C3)C(F)(F)F |
Product Overview
2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide (CAS 374617-57-9), with molecular formula C25H18F6N2O2 and molecular weight 492.13 g/mol. IUPAC: 2-[(4-methylphenyl)methylidene]-N,N'-bis[3-(trifluoromethyl)phenyl]propanediamide.
Chemical Property Profile of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide
Property Insights of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide
The XLogP value of 6.69342 indicates that 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.2 Ų, 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide?
The CAS number of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide is 374617-57-9.
What is the molecular formula of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide?
The molecular formula of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide is C25H18F6N2O2.
What is the molecular weight of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide?
The molecular weight of 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide is 492.13 g/mol.
Where can I buy 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide?
You can request a quote for 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-Methylbenzylidene)-N(1),N(3)-bis(3-(trifluoromethyl)phenyl)malonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.