![1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine structure](/static/products/3745/374559-96-3.webp)
1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine
TL;DR: 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine (CAS 374559-96-3) is a chemical compound with molecular formula C11H9ClF3N3 and molecular weight 275.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-chloro-5-(trifluoromethyl)phenyl]-5-methylpyrazol-3-amine
Also Known As: 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine, 2-(2-Chloro-5-trifluoromethyl-phenyl)-5-methyl-2H-pyrazol-3-ylamine, 2-[2-chloro-5-(trifluoromethyl)phenyl]-5-methylpyrazol-3-amine, 2-[2-chloro-5-(trifluoromethyl)phenyl]-5-methyl-pyrazol-3-amine
| Molecular Formula | C11H9ClF3N3 |
|---|---|
| Molecular Weight | 275.04 g/mol |
| LogP | 3.43512 |
| Topological Polar Surface Area | 43.84 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 275.0437 |
| Heavy Atoms | 18 |
| Complexity | 589.7048 |
Chemical Identifiers
| CAS Number | 374559-96-3 |
|---|---|
| SMILES | CC1=NN(C(=C1)N)C2=C(C=CC(=C2)C(F)(F)F)Cl |
Product Overview
1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine (CAS 374559-96-3), with molecular formula C11H9ClF3N3 and molecular weight 275.04 g/mol. IUPAC: 2-[2-chloro-5-(trifluoromethyl)phenyl]-5-methylpyrazol-3-amine.
Chemical Property Profile of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine
Property Insights of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine
The XLogP value of 3.43512 indicates that 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.84 Ų, 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine?
The CAS number of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine is 374559-96-3.
What is the molecular formula of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine?
The molecular formula of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine is C11H9ClF3N3.
What is the molecular weight of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine?
The molecular weight of 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine is 275.04 g/mol.
Where can I buy 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine?
You can request a quote for 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine?
Yes, KEHONG BIO provides custom synthesis services for 1-[2-chloro-5-(trifluoromethyl)phenyl]-3-methyl-1H-pyrazol-5-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.