CAS 374545-25-2 - C21H18ClN3OS structure

CAS 374545-25-2 - C21H18ClN3OS

TL;DR: CAS 374545-25-2 - C21H18ClN3OS (CAS 374545-25-2) is a chemical compound with molecular formula C21H18ClN3OS and molecular weight 395.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-3-(3-chloro-2-methylanilino)-2-[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile

Also Known As: (2Z)-3-[(3-chloro-2-methylphenyl)amino]-2-[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile

CAS: 374545-25-2
Molecular Formula C21H18ClN3OS
Molecular Weight 395.09 g/mol
LogP 6.1472
Topological Polar Surface Area 57.94 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 395.0859
Heavy Atoms 27
Complexity 1003.01135

Chemical Identifiers

CAS Number 374545-25-2
SMILES CCOC1=CC=C(C=C1)C2=CSC(=N2)/C(=C/NC3=C(C(=CC=C3)Cl)C)/C#N

Product Overview

CAS 374545-25-2 - C21H18ClN3OS (CAS 374545-25-2), with molecular formula C21H18ClN3OS and molecular weight 395.09 g/mol. IUPAC: (E)-3-(3-chloro-2-methylanilino)-2-[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]prop-2-enenitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of CAS 374545-25-2 - C21H18ClN3OS

XLogP
6.1472
TPSA (Topological Polar Surface Area)
57.94
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
27
Complexity
1003.01135
Exact Mass
395.0859
Monoisotopic Mass
395.0859
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of CAS 374545-25-2 - C21H18ClN3OS

The XLogP value of 6.1472 indicates that CAS 374545-25-2 - C21H18ClN3OS is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.94 Ų, CAS 374545-25-2 - C21H18ClN3OS exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, CAS 374545-25-2 - C21H18ClN3OS has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

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Frequently Asked Questions

What is the CAS number of CAS 374545-25-2 - C21H18ClN3OS?

The CAS number of CAS 374545-25-2 - C21H18ClN3OS is 374545-25-2.

What is the molecular formula of CAS 374545-25-2 - C21H18ClN3OS?

The molecular formula of CAS 374545-25-2 - C21H18ClN3OS is C21H18ClN3OS.

What is the molecular weight of CAS 374545-25-2 - C21H18ClN3OS?

The molecular weight of CAS 374545-25-2 - C21H18ClN3OS is 395.09 g/mol.

Where can I buy CAS 374545-25-2 - C21H18ClN3OS?

You can request a quote for CAS 374545-25-2 - C21H18ClN3OS directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for CAS 374545-25-2 - C21H18ClN3OS?

Yes, KEHONG BIO provides custom synthesis services for CAS 374545-25-2 - C21H18ClN3OS and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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