2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine
TL;DR: 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine (CAS 374541-75-0) is a chemical compound with molecular formula C22H18ClN3O2 and molecular weight 391.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine
Also Known As: 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine
| Molecular Formula | C22H18ClN3O2 |
|---|---|
| Molecular Weight | 391.11 g/mol |
| LogP | 5.711 |
| Topological Polar Surface Area | 56.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 391.10876 |
| Heavy Atoms | 28 |
| Complexity | 1130.3799 |
Chemical Identifiers
| CAS Number | 374541-75-0 |
|---|---|
| SMILES | COC1=CC(=C(C=C1)OC)NC2=NC(=NC3=CC=CC=C32)C4=CC=C(C=C4)Cl |
Product Overview
2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine (CAS 374541-75-0), with molecular formula C22H18ClN3O2 and molecular weight 391.11 g/mol. IUPAC: 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine.
Chemical Property Profile of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine
Property Insights of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine
The XLogP value of 5.711 indicates that 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.27 Ų, 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine?
The CAS number of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine is 374541-75-0.
What is the molecular formula of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine?
The molecular formula of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine is C22H18ClN3O2.
What is the molecular weight of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine?
The molecular weight of 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine is 391.11 g/mol.
Where can I buy 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine?
You can request a quote for 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-chlorophenyl)-N-(2,5-dimethoxyphenyl)quinazolin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.