![(2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide structure](/static/products/374/374102-04-2.png)
(2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide
TL;DR: (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide (CAS 374102-04-2) is a chemical compound with molecular formula C22H21N5O5 and molecular weight 435.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[2-[[1-(2-amino-2-oxoethyl)-2-hydroxyindol-3-yl]diazenyl]-2-oxoethyl]-3-(4-methoxyphenyl)prop-2-enamide
Also Known As: (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide, (E)-N-(2-((Z)-2-(1-(2-amino-2-oxoethyl)-2-oxoindolin-3-ylidene)hydrazinyl)-2-oxoethyl)-3-(4-methoxyphenyl)acrylamide, (E)-N-[2-[(2E)-2-[1-(2-amino-2-oxoethyl)-2-oxoindol-3-ylidene]hydrazinyl]-2-oxoethyl]-3-(4-methoxyphenyl)prop-2-enamide, (E)-N-[2-[(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxoindol-3-ylidene]hydrazinyl]-2-oxoethyl]-3-(4-methoxyphenyl)prop-2-enamide
| Molecular Formula | C22H21N5O5 |
|---|---|
| Molecular Weight | 435.15 g/mol |
| LogP | 2.2807 |
| Topological Polar Surface Area | 148.37 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 435.15427 |
| Heavy Atoms | 32 |
| Complexity | 1211.4247 |
Chemical Identifiers
| CAS Number | 374102-04-2 |
|---|---|
| SMILES | COC1=CC=C(C=C1)/C=C/C(=O)NCC(=O)N=NC2=C(N(C3=CC=CC=C32)CC(=O)N)O |
Product Overview
(2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide (CAS 374102-04-2), with molecular formula C22H21N5O5 and molecular weight 435.15 g/mol. IUPAC: (E)-N-[2-[[1-(2-amino-2-oxoethyl)-2-hydroxyindol-3-yl]diazenyl]-2-oxoethyl]-3-(4-methoxyphenyl)prop-2-enamide.
Chemical Property Profile of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide
Property Insights of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide
The XLogP value of 2.2807 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide. The TPSA of 148.37 Ų indicates high polarity, suggesting (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide?
The CAS number of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide is 374102-04-2.
What is the molecular formula of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide?
The molecular formula of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide is C22H21N5O5.
What is the molecular weight of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide?
The molecular weight of (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide is 435.15 g/mol.
Where can I buy (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide?
You can request a quote for (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-N-(2-{(2Z)-2-[1-(2-amino-2-oxoethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]hydrazinyl}-2-oxoethyl)-3-(4-methoxyphenyl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.