![(E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile structure](/static/products/374/374100-21-7.png)
(E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile
TL;DR: (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile (CAS 374100-21-7) is a chemical compound with molecular formula C27H23N3S and molecular weight 421.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-[4-(4-phenylphenyl)-1,3-thiazol-2-yl]-3-(4-propan-2-ylanilino)prop-2-enenitrile
Also Known As: (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile, (E)-2-[4-(4-phenylphenyl)-1,3-thiazol-2-yl]-3-(4-propan-2-ylanilino)prop-2-enenitrile, (2E)-2-[4-(biphenyl-4-yl)-1,3-thiazol-2-yl]-3-{[4-(propan-2-yl)phenyl]amino}prop-2-enenitrile
| Molecular Formula | C27H23N3S |
|---|---|
| Molecular Weight | 421.16 g/mol |
| LogP | 7.57708 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 421.16125 |
| Heavy Atoms | 31 |
| Complexity | 1212.229 |
Chemical Identifiers
| CAS Number | 374100-21-7 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)N/C=C(\C#N)/C2=NC(=CS2)C3=CC=C(C=C3)C4=CC=CC=C4 |
Product Overview
(E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile (CAS 374100-21-7), with molecular formula C27H23N3S and molecular weight 421.16 g/mol. IUPAC: (E)-2-[4-(4-phenylphenyl)-1,3-thiazol-2-yl]-3-(4-propan-2-ylanilino)prop-2-enenitrile.
Chemical Property Profile of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile
Property Insights of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile
The XLogP value of 7.57708 indicates that (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile?
The CAS number of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile is 374100-21-7.
What is the molecular formula of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile?
The molecular formula of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile is C27H23N3S.
What is the molecular weight of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile?
The molecular weight of (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile is 421.16 g/mol.
Where can I buy (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile?
You can request a quote for (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-([1,1'-biphenyl]-4-yl)thiazol-2-yl)-3-((4-isopropylphenyl)amino)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.