![5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine structure](/static/products/374/374087-74-8.png)
5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine
TL;DR: 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine (CAS 374087-74-8) is a chemical compound with molecular formula C22H22N4O2S and molecular weight 406.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-(furan-2-yl)-N-(oxolan-2-ylmethyl)-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12,14,16-hexaen-13-amine
Also Known As: 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine, 5-(furan-2-yl)-N-(tetrahydrofuran-2-ylmethyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine, N-[5-(2-FURYL)-1,2,3,4-TETRAHYDROPYRIMIDO[4',5':4,5]THIENO[2,3-C]ISOQUINOLIN-8-YL]-N-TETRAHYDRO-2-FURANYLMETHYLAMINE
| Molecular Formula | C22H22N4O2S |
|---|---|
| Molecular Weight | 406.15 g/mol |
| LogP | 4.9692 |
| Topological Polar Surface Area | 73.07 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 406.14636 |
| Heavy Atoms | 29 |
| Complexity | 1178.9344 |
Chemical Identifiers
| CAS Number | 374087-74-8 |
|---|---|
| SMILES | C1CCC2=C(C1)C3=C(N=C2C4=CC=CO4)SC5=C3N=CN=C5NCC6CCCO6 |
Product Overview
5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine (CAS 374087-74-8), with molecular formula C22H22N4O2S and molecular weight 406.15 g/mol. IUPAC: 8-(furan-2-yl)-N-(oxolan-2-ylmethyl)-11-thia-9,14,16-triazatetracyclo[8.7.0.02,7.012,17]heptadeca-1,7,9,12,14,16-hexaen-13-amine.
Chemical Property Profile of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine
Property Insights of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine
The XLogP value of 4.9692 indicates that 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.07 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine. Following Lipinski's Rule of Five, 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine?
The CAS number of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine is 374087-74-8.
What is the molecular formula of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine?
The molecular formula of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine is C22H22N4O2S.
What is the molecular weight of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine?
The molecular weight of 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine is 406.15 g/mol.
Where can I buy 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine?
You can request a quote for 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine?
Yes, KEHONG BIO provides custom synthesis services for 5-(furan-2-yl)-N-((tetrahydrofuran-2-yl)methyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.