AE-848/11489143
TL;DR: AE-848/11489143 (CAS 373617-16-4) is a chemical compound with molecular formula C21H18N2O3S and molecular weight 378.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-methoxyphenyl)prop-2-enenitrile
Also Known As: AE-848/11489143, (2Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-methoxyphenyl)prop-2-enenitrile, (Z)-2-(4-(3,4-dimethoxyphenyl)thiazol-2-yl)-3-(3-methoxyphenyl)acrylonitrile, (Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-methoxyphenyl)prop-2-enenitrile, 2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-methoxyphenyl)acrylonitrile
| Molecular Formula | C21H18N2O3S |
|---|---|
| Molecular Weight | 378.10 g/mol |
| LogP | 4.90008 |
| Topological Polar Surface Area | 64.37 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 378.10382 |
| Heavy Atoms | 27 |
| Complexity | 1018.26135 |
Chemical Identifiers
| CAS Number | 373617-16-4 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)C2=CSC(=N2)/C(=C\C3=CC(=CC=C3)OC)/C#N)OC |
Product Overview
AE-848/11489143 (CAS 373617-16-4), with molecular formula C21H18N2O3S and molecular weight 378.10 g/mol. IUPAC: (Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-methoxyphenyl)prop-2-enenitrile.
Chemical Property Profile of AE-848/11489143
Property Insights of AE-848/11489143
The XLogP value of 4.90008 indicates that AE-848/11489143 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.37 Ų falls within the moderate polarity range, balancing permeability and solubility for AE-848/11489143. Following Lipinski's Rule of Five, AE-848/11489143 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AE-848/11489143?
The CAS number of AE-848/11489143 is 373617-16-4.
What is the molecular formula of AE-848/11489143?
The molecular formula of AE-848/11489143 is C21H18N2O3S.
What is the molecular weight of AE-848/11489143?
The molecular weight of AE-848/11489143 is 378.10 g/mol.
Where can I buy AE-848/11489143?
You can request a quote for AE-848/11489143 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AE-848/11489143?
Yes, KEHONG BIO provides custom synthesis services for AE-848/11489143 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.