(E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate
TL;DR: (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate (CAS 373615-83-9) is a chemical compound with molecular formula C22H18N2O5S and molecular weight 422.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 2-[[(E)-2-cyano-3-(furan-2-yl)prop-2-enoyl]amino]-4-(4-methoxyphenyl)thiophene-3-carboxylate
Also Known As: (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate, F1589-0563, ETHYL 2-[(2E)-2-CYANO-3-(FURAN-2-YL)PROP-2-ENAMIDO]-4-(4-METHOXYPHENYL)THIOPHENE-3-CARBOXYLATE, ethyl 2-[[(E)-2-cyano-3-(furan-2-yl)prop-2-enoyl]amino]-4-(4-methoxyphenyl)thiophene-3-carboxylate, ethyl 2-((2E)-2-cyano-3-(2-furyl)prop-2-enoylamino)-4-(4-methoxyphenyl)thiophe ne-3-carboxylate
| Molecular Formula | C22H18N2O5S |
|---|---|
| Molecular Weight | 422.09 g/mol |
| LogP | 4.73908 |
| Topological Polar Surface Area | 101.56 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 422.09363 |
| Heavy Atoms | 30 |
| Complexity | 1105.6069 |
Chemical Identifiers
| CAS Number | 373615-83-9 |
|---|---|
| SMILES | CCOC(=O)C1=C(SC=C1C2=CC=C(C=C2)OC)NC(=O)/C(=C/C3=CC=CO3)/C#N |
Product Overview
(E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate (CAS 373615-83-9), with molecular formula C22H18N2O5S and molecular weight 422.09 g/mol. IUPAC: ethyl 2-[[(E)-2-cyano-3-(furan-2-yl)prop-2-enoyl]amino]-4-(4-methoxyphenyl)thiophene-3-carboxylate.
Chemical Property Profile of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate
Property Insights of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate
The XLogP value of 4.73908 indicates that (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.56 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate. Following Lipinski's Rule of Five, (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate?
The CAS number of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate is 373615-83-9.
What is the molecular formula of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate?
The molecular formula of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate is C22H18N2O5S.
What is the molecular weight of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate?
The molecular weight of (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate is 422.09 g/mol.
Where can I buy (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate?
You can request a quote for (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (E)-ethyl 2-(2-cyano-3-(furan-2-yl)acrylamido)-4-(4-methoxyphenyl)thiophene-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.