![(2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile structure](/static/products/373/373613-48-0.png)
(2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile
TL;DR: (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile (CAS 373613-48-0) is a chemical compound with molecular formula C18H12ClN3S and molecular weight 337.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-3-anilino-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile
Also Known As: (Z)-2-(4-(4-chlorophenyl)thiazol-2-yl)-3-(phenylamino)acrylonitrile, (Z)-3-anilino-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile, (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile, 2-Thiazoleacetonitrile, 4-(4-chlorophenyl)-alpha-[(phenylamino)methylene]-, (alphaZ)-
| Molecular Formula | C18H12ClN3S |
|---|---|
| Molecular Weight | 337.04 g/mol |
| LogP | 5.44008 |
| Topological Polar Surface Area | 48.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 337.04404 |
| Heavy Atoms | 23 |
| Complexity | 861.2873 |
Chemical Identifiers
| CAS Number | 373613-48-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)N/C=C(/C#N)\C2=NC(=CS2)C3=CC=C(C=C3)Cl |
Product Overview
(2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile (CAS 373613-48-0), with molecular formula C18H12ClN3S and molecular weight 337.04 g/mol. IUPAC: (Z)-3-anilino-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile.
Chemical Property Profile of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile
Property Insights of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile
The XLogP value of 5.44008 indicates that (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.71 Ų, (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile?
The CAS number of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile is 373613-48-0.
What is the molecular formula of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile?
The molecular formula of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile is C18H12ClN3S.
What is the molecular weight of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile?
The molecular weight of (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile is 337.04 g/mol.
Where can I buy (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile?
You can request a quote for (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile?
Yes, KEHONG BIO provides custom synthesis services for (2Z)-2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(phenylamino)prop-2-enenitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.