Pyrimethamine; sulfadoxine
TL;DR: Pyrimethamine; sulfadoxine (CAS 37338-39-9) is a chemical compound with molecular formula C24H27ClN8O4S and molecular weight 558.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide;5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
Also Known As: Fansidar, Suldox, Fansidar (TN), sulfadoxine-pyrimethamine, Pyrimethamine-sulfadoxine
| Molecular Formula | C24H27ClN8O4S |
|---|---|
| Molecular Weight | 558.16 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 203.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 7 |
| Exact Mass | 558.15643 |
| Heavy Atoms | 38 |
| Complexity | 662.0 |
Chemical Identifiers
| CAS Number | 37338-39-9 |
|---|---|
| SMILES | CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl.COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N |
| InChIKey | LUBUTTBEBGYNJN-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Pyrimethamine; sulfadoxine (CAS 37338-39-9), with molecular formula C24H27ClN8O4S and molecular weight 558.16 g/mol. IUPAC: 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide;5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine.
Chemical Property Profile of Pyrimethamine; sulfadoxine
Property Insights of Pyrimethamine; sulfadoxine
The XLogP value of 3.4 indicates that Pyrimethamine; sulfadoxine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 203.0 Ų indicates high polarity, suggesting Pyrimethamine; sulfadoxine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyrimethamine; sulfadoxine has 4 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyrimethamine; sulfadoxine?
The CAS number of Pyrimethamine; sulfadoxine is 37338-39-9.
What is the molecular formula of Pyrimethamine; sulfadoxine?
The molecular formula of Pyrimethamine; sulfadoxine is C24H27ClN8O4S.
What is the molecular weight of Pyrimethamine; sulfadoxine?
The molecular weight of Pyrimethamine; sulfadoxine is 558.16 g/mol.
Where can I buy Pyrimethamine; sulfadoxine?
You can request a quote for Pyrimethamine; sulfadoxine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyrimethamine; sulfadoxine?
Yes, KEHONG BIO provides custom synthesis services for Pyrimethamine; sulfadoxine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.