N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide
TL;DR: N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide (CAS 373375-47-4) is a chemical compound with molecular formula C20H20N4O4S and molecular weight 412.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-ethoxyphenyl)-6-methyl-4-(3-nitrophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide
Also Known As: N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide, N-(2-ethoxyphenyl)-6-methyl-4-(3-nitrophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide, N-(2-ethoxyphenyl)-6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
| Molecular Formula | C20H20N4O4S |
|---|---|
| Molecular Weight | 412.12 g/mol |
| LogP | 3.425 |
| Topological Polar Surface Area | 105.53 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 412.1205 |
| Heavy Atoms | 29 |
| Complexity | 1005.48065 |
Chemical Identifiers
| CAS Number | 373375-47-4 |
|---|---|
| SMILES | CCOC1=CC=CC=C1NC(=O)C2=C(NC(=S)NC2C3=CC(=CC=C3)[N+](=O)[O-])C |
Product Overview
N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide (CAS 373375-47-4), with molecular formula C20H20N4O4S and molecular weight 412.12 g/mol. IUPAC: N-(2-ethoxyphenyl)-6-methyl-4-(3-nitrophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxamide.
Chemical Property Profile of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide
Property Insights of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide
The XLogP value of 3.425 indicates that N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 105.53 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide. Following Lipinski's Rule of Five, N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide?
The CAS number of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide is 373375-47-4.
What is the molecular formula of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide?
The molecular formula of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide is C20H20N4O4S.
What is the molecular weight of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide?
The molecular weight of N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide is 412.12 g/mol.
Where can I buy N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide?
You can request a quote for N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2-ethoxyphenyl)-4-methyl-6-(3-nitrophenyl)-2-sulfanyl-1,6-dihydropyrimidine-5-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.