(E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate structure

(E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate

TL;DR: (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate (CAS 373375-45-2) is a chemical compound with molecular formula C27H20N2O4S and molecular weight 468.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 2-[[(E)-2-cyano-3-(5-phenylfuran-2-yl)prop-2-enoyl]amino]-4-phenylthiophene-3-carboxylate

Also Known As: (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate, ethyl 2-[(2E)-2-cyano-3-(5-phenyl(2-furyl))prop-2-enoylamino]-4-phenylthiophen e-3-carboxylate, ethyl 2-[[(E)-2-cyano-3-(5-phenylfuran-2-yl)prop-2-enoyl]amino]-4-phenylthiophene-3-carboxylate, Ethyl 2-[[2-cyano-3-(5-phenyl-2-furyl)prop-2-enoyl]amino]-4-phenyl-thiophene-3-carboxylate, ethyl 2-{[(2E)-2-cyano-3-(5-phenylfuran-2-yl)prop-2-enoyl]amino}-4-phenylthiophene-3-carboxylate

CAS: 373375-45-2
Molecular Formula C27H20N2O4S
Molecular Weight 468.11 g/mol
LogP 6.39748
Topological Polar Surface Area 92.33 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 7
Exact Mass 468.11438
Heavy Atoms 34
Complexity 1379.0183

Chemical Identifiers

CAS Number 373375-45-2
SMILES CCOC(=O)C1=C(SC=C1C2=CC=CC=C2)NC(=O)/C(=C/C3=CC=C(O3)C4=CC=CC=C4)/C#N

Product Overview

(E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate (CAS 373375-45-2), with molecular formula C27H20N2O4S and molecular weight 468.11 g/mol. IUPAC: ethyl 2-[[(E)-2-cyano-3-(5-phenylfuran-2-yl)prop-2-enoyl]amino]-4-phenylthiophene-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate

XLogP
6.39748
TPSA (Topological Polar Surface Area)
92.33
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
7
Heavy Atoms
34
Complexity
1379.0183
Exact Mass
468.11438
Monoisotopic Mass
468.11438
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate

The XLogP value of 6.39748 indicates that (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 92.33 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate. Following Lipinski's Rule of Five, (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate?

The CAS number of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate is 373375-45-2.

What is the molecular formula of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate?

The molecular formula of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate is C27H20N2O4S.

What is the molecular weight of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate?

The molecular weight of (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate is 468.11 g/mol.

Where can I buy (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate?

You can request a quote for (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate?

Yes, KEHONG BIO provides custom synthesis services for (E)-ethyl 2-(2-cyano-3-(5-phenylfuran-2-yl)acrylamido)-4-phenylthiophene-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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