(Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile
TL;DR: (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile (CAS 373374-87-9) is a chemical compound with molecular formula C20H16ClN3O2S and molecular weight 397.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-3-(4-chloro-2,5-dimethoxyanilino)-2-(4-phenyl-1,3-thiazol-2-yl)prop-2-enenitrile
Also Known As: (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile, (2Z)-3-[(4-chloro-2,5-dimethoxyphenyl)amino]-2-(4-phenyl-1,3-thiazol-2-yl)prop-2-enenitrile, F0760-2149, (Z)-3-(4-chloro-2,5-dimethoxyanilino)-2-(4-phenyl-1,3-thiazol-2-yl)prop-2-enenitrile
| Molecular Formula | C20H16ClN3O2S |
|---|---|
| Molecular Weight | 397.07 g/mol |
| LogP | 5.45728 |
| Topological Polar Surface Area | 67.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 397.0652 |
| Heavy Atoms | 27 |
| Complexity | 1009.81146 |
Chemical Identifiers
| CAS Number | 373374-87-9 |
|---|---|
| SMILES | COC1=CC(=C(C=C1N/C=C(/C#N)\C2=NC(=CS2)C3=CC=CC=C3)OC)Cl |
Product Overview
(Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile (CAS 373374-87-9), with molecular formula C20H16ClN3O2S and molecular weight 397.07 g/mol. IUPAC: (Z)-3-(4-chloro-2,5-dimethoxyanilino)-2-(4-phenyl-1,3-thiazol-2-yl)prop-2-enenitrile.
Chemical Property Profile of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile
Property Insights of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile
The XLogP value of 5.45728 indicates that (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.17 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile. Following Lipinski's Rule of Five, (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile?
The CAS number of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile is 373374-87-9.
What is the molecular formula of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile?
The molecular formula of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile is C20H16ClN3O2S.
What is the molecular weight of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile?
The molecular weight of (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile is 397.07 g/mol.
Where can I buy (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile?
You can request a quote for (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for (Z)-3-((4-chloro-2,5-dimethoxyphenyl)amino)-2-(4-phenylthiazol-2-yl)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.