![(5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione structure](/static/products/373/373371-64-3.png)
(5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione
TL;DR: (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione (CAS 373371-64-3) is a chemical compound with molecular formula C19H13F3N2O4 and molecular weight 390.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(4-methoxyphenyl)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione
Also Known As: (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione, (5E)-5-[(4-methoxyphenyl)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione, (E)-5-(4-methoxybenzylidene)-1-(3-(trifluoromethyl)phenyl)pyrimidine-2,4,6(1H,3H,5H)-trione
| Molecular Formula | C19H13F3N2O4 |
|---|---|
| Molecular Weight | 390.08 g/mol |
| LogP | 3.3804 |
| Topological Polar Surface Area | 75.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 390.08273 |
| Heavy Atoms | 28 |
| Complexity | 981.4184 |
Chemical Identifiers
| CAS Number | 373371-64-3 |
|---|---|
| SMILES | COC1=CC=C(C=C1)/C=C/2\C(=O)NC(=O)N(C2=O)C3=CC=CC(=C3)C(F)(F)F |
Product Overview
(5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione (CAS 373371-64-3), with molecular formula C19H13F3N2O4 and molecular weight 390.08 g/mol. IUPAC: (5E)-5-[(4-methoxyphenyl)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione.
Chemical Property Profile of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione
Property Insights of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione
The XLogP value of 3.3804 indicates that (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.71 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione. Following Lipinski's Rule of Five, (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione?
The CAS number of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione is 373371-64-3.
What is the molecular formula of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione?
The molecular formula of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione is C19H13F3N2O4.
What is the molecular weight of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione?
The molecular weight of (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione is 390.08 g/mol.
Where can I buy (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione?
You can request a quote for (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione?
Yes, KEHONG BIO provides custom synthesis services for (5E)-2-hydroxy-5-(4-methoxybenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-4,6(1H,5H)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.