阿普拉霉素
TL;DR: 阿普拉霉素 (CAS 37322-81-9) is a chemical compound with molecular formula C21H41N5O11 and molecular weight 539.28 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
阿普拉霉素
(2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol
Also Known As: apramycin, Nebramycin II, Apramicina, Apramycine, Apramycinum
| Molecular Formula | C21H41N5O11 |
|---|---|
| Molecular Weight | 539.28 g/mol |
| LogP | -6.9493 |
| Topological Polar Surface Area | 283.64 Ų |
| Hydrogen Bond Donors | 11 |
| Hydrogen Bond Acceptors | 16 |
| Rotatable Bonds | 6 |
| Exact Mass | 539.2803 |
| Heavy Atoms | 37 |
| Complexity | 755.6746 |
Chemical Identifiers
| CAS Number | 37322-81-9 |
|---|---|
| SMILES | CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H]([C@H](O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O |
Product Overview
阿普拉霉素 (CAS 37322-81-9), with molecular formula C21H41N5O11 and molecular weight 539.28 g/mol. IUPAC: (2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol.
Chemical Property Profile of 阿普拉霉素
Property Insights of 阿普拉霉素
The XLogP value of -6.9493 indicates that 阿普拉霉素 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 283.64 Ų indicates high polarity, suggesting 阿普拉霉素 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 阿普拉霉素 has 11 hydrogen bond donor(s) and 16 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 阿普拉霉素?
The CAS number of 阿普拉霉素 is 37322-81-9.
What is the molecular formula of 阿普拉霉素?
The molecular formula of 阿普拉霉素 is C21H41N5O11.
What is the molecular weight of 阿普拉霉素?
The molecular weight of 阿普拉霉素 is 539.28 g/mol.
Where can I buy 阿普拉霉素?
You can request a quote for 阿普拉霉素 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 阿普拉霉素?
Yes, KEHONG BIO provides custom synthesis services for 阿普拉霉素 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.