N,N,N',N'-Tetramethylphosphoramide structure

N,N,N',N'-Tetramethylphosphoramide

TL;DR: N,N,N',N'-Tetramethylphosphoramide (CAS 3732-86-3) is a chemical compound with molecular formula C4H14N3OP and molecular weight 151.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[amino(dimethylamino)phosphoryl]-N-methylmethanamine

Also Known As: tetramethyl-phosphoramide, N,N,N',N'-Tetramethylphosphoramide, N,N-Dimethyl-dimethylphosphoric amide, ((CH3)2N)2(NH2)PO, Aminobis(dimethylamino)phosphine oxide

CAS: 3732-86-3
Molecular Formula C4H14N3OP
Molecular Weight 151.09 g/mol
LogP -1.4
Topological Polar Surface Area 49.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 151.08745
Heavy Atoms 9
Complexity 122.0

Chemical Identifiers

CAS Number 3732-86-3
SMILES CN(C)P(=O)(N)N(C)C
InChIKey HTFUZOUJKZBUAL-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Biotechnology (5 patents) Heterocyclic Building Blocks (14 patents) Pharmaceutical Intermediates (4 patents) Polymer Intermediates (4 patents)

Product Overview

N,N,N',N'-Tetramethylphosphoramide (CAS 3732-86-3), with molecular formula C4H14N3OP and molecular weight 151.09 g/mol. IUPAC: N-[amino(dimethylamino)phosphoryl]-N-methylmethanamine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of N,N,N',N'-Tetramethylphosphoramide

XLogP
-1.4
TPSA (Topological Polar Surface Area)
49.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
9
Complexity
122.0
Exact Mass
151.08745
Monoisotopic Mass
151.08745
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N,N,N',N'-Tetramethylphosphoramide

The XLogP value of -1.4 indicates that N,N,N',N'-Tetramethylphosphoramide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 49.6 Ų, N,N,N',N'-Tetramethylphosphoramide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N,N,N',N'-Tetramethylphosphoramide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N,N,N',N'-Tetramethylphosphoramide?

The CAS number of N,N,N',N'-Tetramethylphosphoramide is 3732-86-3.

What is the molecular formula of N,N,N',N'-Tetramethylphosphoramide?

The molecular formula of N,N,N',N'-Tetramethylphosphoramide is C4H14N3OP.

What is the molecular weight of N,N,N',N'-Tetramethylphosphoramide?

The molecular weight of N,N,N',N'-Tetramethylphosphoramide is 151.09 g/mol.

Where can I buy N,N,N',N'-Tetramethylphosphoramide?

You can request a quote for N,N,N',N'-Tetramethylphosphoramide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N,N,N',N'-Tetramethylphosphoramide?

Yes, KEHONG BIO provides custom synthesis services for N,N,N',N'-Tetramethylphosphoramide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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