(Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile
TL;DR: (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile (CAS 372979-83-4) is a chemical compound with molecular formula C19H13N3O4S and molecular weight 379.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-3-(3-hydroxy-4-methoxyphenyl)-2-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile
Also Known As: (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile, (2Z)-3-(3-hydroxy-4-methoxyphenyl)-2-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile, (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile
| Molecular Formula | C19H13N3O4S |
|---|---|
| Molecular Weight | 379.06 g/mol |
| LogP | 4.49668 |
| Topological Polar Surface Area | 109.28 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 379.06268 |
| Heavy Atoms | 27 |
| Complexity | 1082.554 |
Chemical Identifiers
| CAS Number | 372979-83-4 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)/C=C(/C#N)\C2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])O |
Product Overview
(Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile (CAS 372979-83-4), with molecular formula C19H13N3O4S and molecular weight 379.06 g/mol. IUPAC: (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]prop-2-enenitrile.
Chemical Property Profile of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile
Property Insights of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile
The XLogP value of 4.49668 indicates that (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 109.28 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile. Following Lipinski's Rule of Five, (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile?
The CAS number of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile is 372979-83-4.
What is the molecular formula of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile?
The molecular formula of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile is C19H13N3O4S.
What is the molecular weight of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile?
The molecular weight of (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile is 379.06 g/mol.
Where can I buy (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile?
You can request a quote for (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-(4-(3-nitrophenyl)thiazol-2-yl)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.