![4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide structure](/static/products/372/372977-67-8.png)
4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide
TL;DR: 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide (CAS 372977-67-8) is a chemical compound with molecular formula C25H23F3N2O2S and molecular weight 472.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-tert-butyl-N-[(E)-3-oxo-1-thiophen-2-yl-3-[3-(trifluoromethyl)anilino]prop-1-en-2-yl]benzamide
Also Known As: 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide, (E)-4-(tert-butyl)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)benzamide, 4-tert-butyl-N-[(1E)-3-oxo-1-(thiophen-2-yl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-1-en-2-yl]benzamide, 4-tert-butyl-N-[(E)-3-oxo-1-thiophen-2-yl-3-[3-(trifluoromethyl)anilino]prop-1-en-2-yl]benzamide
| Molecular Formula | C25H23F3N2O2S |
|---|---|
| Molecular Weight | 472.14 g/mol |
| LogP | 6.474 |
| Topological Polar Surface Area | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 472.14322 |
| Heavy Atoms | 33 |
| Complexity | 1159.6079 |
Chemical Identifiers
| CAS Number | 372977-67-8 |
|---|---|
| SMILES | CC(C)(C)C1=CC=C(C=C1)C(=O)N/C(=C/C2=CC=CS2)/C(=O)NC3=CC=CC(=C3)C(F)(F)F |
Product Overview
4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide (CAS 372977-67-8), with molecular formula C25H23F3N2O2S and molecular weight 472.14 g/mol. IUPAC: 4-tert-butyl-N-[(E)-3-oxo-1-thiophen-2-yl-3-[3-(trifluoromethyl)anilino]prop-1-en-2-yl]benzamide.
Chemical Property Profile of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide
Property Insights of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide
The XLogP value of 6.474 indicates that 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.2 Ų, 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide?
The CAS number of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide is 372977-67-8.
What is the molecular formula of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide?
The molecular formula of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide is C25H23F3N2O2S.
What is the molecular weight of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide?
The molecular weight of 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide is 472.14 g/mol.
Where can I buy 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide?
You can request a quote for 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide?
Yes, KEHONG BIO provides custom synthesis services for 4-tert-butyl-N-[2-thiophen-2-yl-1-[[3-(trifluoromethyl)phenyl]carbamoyl]ethenyl]benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.