AE-848/11489167
TL;DR: AE-848/11489167 (CAS 372505-99-2) is a chemical compound with molecular formula C21H18N2O4S and molecular weight 394.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enenitrile
Also Known As: AE-848/11489167, (Z)-2-(4-(3,4-dimethoxyphenyl)thiazol-2-yl)-3-(3-hydroxy-4-methoxyphenyl)acrylonitrile, 2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-hydroxy-4-methoxyphenyl)acrylonitrile, (2Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enenitrile, (Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enenitrile
| Molecular Formula | C21H18N2O4S |
|---|---|
| Molecular Weight | 394.10 g/mol |
| LogP | 4.60568 |
| Topological Polar Surface Area | 84.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 394.09872 |
| Heavy Atoms | 28 |
| Complexity | 1066.5078 |
Chemical Identifiers
| CAS Number | 372505-99-2 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)/C=C(/C#N)\C2=NC(=CS2)C3=CC(=C(C=C3)OC)OC)O |
Product Overview
AE-848/11489167 (CAS 372505-99-2), with molecular formula C21H18N2O4S and molecular weight 394.10 g/mol. IUPAC: (Z)-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enenitrile.
Chemical Property Profile of AE-848/11489167
Property Insights of AE-848/11489167
The XLogP value of 4.60568 indicates that AE-848/11489167 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.6 Ų falls within the moderate polarity range, balancing permeability and solubility for AE-848/11489167. Following Lipinski's Rule of Five, AE-848/11489167 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AE-848/11489167?
The CAS number of AE-848/11489167 is 372505-99-2.
What is the molecular formula of AE-848/11489167?
The molecular formula of AE-848/11489167 is C21H18N2O4S.
What is the molecular weight of AE-848/11489167?
The molecular weight of AE-848/11489167 is 394.10 g/mol.
Where can I buy AE-848/11489167?
You can request a quote for AE-848/11489167 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AE-848/11489167?
Yes, KEHONG BIO provides custom synthesis services for AE-848/11489167 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.