![(5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione structure](/static/products/372/372500-91-9.png)
(5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione
TL;DR: (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 372500-91-9) is a chemical compound with molecular formula C18H9Cl2F3N2O3 and molecular weight 427.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(2,6-dichlorophenyl)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione
Also Known As: (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione, (5E)-5-[(2,6-dichlorophenyl)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione, (E)-5-(2,6-dichlorobenzylidene)-1-(3-(trifluoromethyl)phenyl)pyrimidine-2,4,6(1H,3H,5H)-trione, 5-[(2,6-dichlorophenyl)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione
| Molecular Formula | C18H9Cl2F3N2O3 |
|---|---|
| Molecular Weight | 427.99 g/mol |
| LogP | 4.6786 |
| Topological Polar Surface Area | 66.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 427.99423 |
| Heavy Atoms | 28 |
| Complexity | 1014.72614 |
Chemical Identifiers
| CAS Number | 372500-91-9 |
|---|---|
| SMILES | C1=CC(=CC(=C1)N2C(=O)/C(=C/C3=C(C=CC=C3Cl)Cl)/C(=O)NC2=O)C(F)(F)F |
Product Overview
(5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 372500-91-9), with molecular formula C18H9Cl2F3N2O3 and molecular weight 427.99 g/mol. IUPAC: (5E)-5-[(2,6-dichlorophenyl)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione.
Chemical Property Profile of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione
Property Insights of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione
The XLogP value of 4.6786 indicates that (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione. Following Lipinski's Rule of Five, (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione?
The CAS number of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione is 372500-91-9.
What is the molecular formula of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione?
The molecular formula of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione is C18H9Cl2F3N2O3.
What is the molecular weight of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione?
The molecular weight of (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione is 427.99 g/mol.
Where can I buy (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione?
You can request a quote for (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione?
Yes, KEHONG BIO provides custom synthesis services for (5E)-5-(2,6-dichlorobenzylidene)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.