5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one
TL;DR: 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one (CAS 372500-41-9) is a chemical compound with molecular formula C17H14BrClN2O and molecular weight 376.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-bromo-4-chloro-2-(2-phenylethyliminomethyl)-1H-indol-3-ol
Also Known As: 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one, (Z)-5-bromo-4-chloro-2-((phenethylamino)methylene)indolin-3-one, 5-bromo-4-chloro-2-[(phenethylamino)methylidene]-1H-indol-3-one, (2E)-5-bromo-4-chloro-2-[(phenethylamino)methylidene]-1H-indol-3-one, (2E)-5-BROMO-4-CHLORO-2-{[(2-PHENYLETHYL)AMINO]METHYLIDENE}-2,3-DIHYDRO-1H-INDOL-3-ONE
| Molecular Formula | C17H14BrClN2O |
|---|---|
| Molecular Weight | 376.00 g/mol |
| LogP | 4.9 |
| Topological Polar Surface Area | 48.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 375.9978 |
| Heavy Atoms | 22 |
| Complexity | 389.0 |
Chemical Identifiers
| CAS Number | 372500-41-9 |
|---|---|
| SMILES | C1=CC=C(C=C1)CCN=CC2=C(C3=C(N2)C=CC(=C3Cl)Br)O |
| InChIKey | VHXAUSJWMJRONK-UHFFFAOYSA-N |
Product Overview
5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one (CAS 372500-41-9), with molecular formula C17H14BrClN2O and molecular weight 376.00 g/mol. IUPAC: 5-bromo-4-chloro-2-(2-phenylethyliminomethyl)-1H-indol-3-ol.
Chemical Property Profile of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one
Property Insights of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one
The XLogP value of 4.9 indicates that 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.4 Ų, 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one?
The CAS number of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one is 372500-41-9.
What is the molecular formula of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one?
The molecular formula of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one is C17H14BrClN2O.
What is the molecular weight of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one?
The molecular weight of 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one is 376.00 g/mol.
Where can I buy 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one?
You can request a quote for 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one?
Yes, KEHONG BIO provides custom synthesis services for 5-Bromo-4-chloro-2-(phenethylamino-methylene)-1,2-dihydro-indol-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.