1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione
TL;DR: 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione (CAS 372183-30-7) is a chemical compound with molecular formula C18H11Cl4FN2O2 and molecular weight 445.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1,3-bis[(2,6-dichlorophenyl)methyl]-5-fluoropyrimidine-2,4-dione
Also Known As: NCI60_027884, AE-641/10126046, 1,3-bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione, 1,3-Bis(2,6-dichlorobenzyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione, 1,3-bis[(2,6-dichlorophenyl)methyl]-5-fluoro-pyrimidine-2,4-dione
| Molecular Formula | C18H11Cl4FN2O2 |
|---|---|
| Molecular Weight | 445.96 g/mol |
| LogP | 5.2 |
| Topological Polar Surface Area | 40.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 445.95587 |
| Heavy Atoms | 27 |
| Complexity | 600.0 |
Chemical Identifiers
| CAS Number | 372183-30-7 |
|---|---|
| SMILES | C1=CC(=C(C(=C1)Cl)CN2C=C(C(=O)N(C2=O)CC3=C(C=CC=C3Cl)Cl)F)Cl |
| InChIKey | HZHUEKUZQLHQCE-UHFFFAOYSA-N |
Product Overview
1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione (CAS 372183-30-7), with molecular formula C18H11Cl4FN2O2 and molecular weight 445.96 g/mol. IUPAC: 1,3-bis[(2,6-dichlorophenyl)methyl]-5-fluoropyrimidine-2,4-dione.
Chemical Property Profile of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione
Property Insights of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione
The XLogP value of 5.2 indicates that 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.6 Ų, 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione?
The CAS number of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione is 372183-30-7.
What is the molecular formula of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione?
The molecular formula of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione is C18H11Cl4FN2O2.
What is the molecular weight of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione?
The molecular weight of 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione is 445.96 g/mol.
Where can I buy 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione?
You can request a quote for 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione?
Yes, KEHONG BIO provides custom synthesis services for 1,3-Bis(2,6-dichlorobenzyl)-5-fluoropyrimidine-2,4(1h,3h)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.