![8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile structure](/static/products/3721/372154-78-4.webp)
8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile
TL;DR: 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile (CAS 372154-78-4) is a chemical compound with molecular formula C19H22N4OS and molecular weight 354.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-(furan-2-yl)-3,3-dimethyl-6-piperazin-1-yl-1,4-dihydrothiopyrano[3,4-c]pyridine-5-carbonitrile
Also Known As: 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile, 8-(furan-2-yl)-3,3-dimethyl-6-piperazin-1-yl-1,4-dihydrothiopyrano[3,4-c]pyridine-5-carbonitrile, 1H-Thiopyrano[3,4-c]pyridine-5-carbonitrile, 3,4-dihydro-8-(2-furyl)-3,3-dimethyl-6-(1-piperazinyl)-, 8-(2-Furyl)-3,3-dimethyl-6-(1-piperazinyl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile #, 8-Furan-2-yl-3,3-dimethyl-6-piperazin-1-yl-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile
| Molecular Formula | C19H22N4OS |
|---|---|
| Molecular Weight | 354.15 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 90.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 354.15143 |
| Heavy Atoms | 25 |
| Complexity | 527.0 |
Chemical Identifiers
| CAS Number | 372154-78-4 |
|---|---|
| SMILES | CC1(CC2=C(CS1)C(=NC(=C2C#N)N3CCNCC3)C4=CC=CO4)C |
| InChIKey | NFIWEZFZLNMHDM-UHFFFAOYSA-N |
Product Overview
8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile (CAS 372154-78-4), with molecular formula C19H22N4OS and molecular weight 354.15 g/mol. IUPAC: 8-(furan-2-yl)-3,3-dimethyl-6-piperazin-1-yl-1,4-dihydrothiopyrano[3,4-c]pyridine-5-carbonitrile.
Chemical Property Profile of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile
Property Insights of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile. The TPSA of 90.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile. Following Lipinski's Rule of Five, 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile?
The CAS number of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile is 372154-78-4.
What is the molecular formula of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile?
The molecular formula of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile is C19H22N4OS.
What is the molecular weight of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile?
The molecular weight of 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile is 354.15 g/mol.
Where can I buy 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile?
You can request a quote for 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile?
Yes, KEHONG BIO provides custom synthesis services for 8-(furan-2-yl)-3,3-dimethyl-6-(piperazin-1-yl)-3,4-dihydro-1H-thiopyrano[3,4-c]pyridine-5-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.