6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile
TL;DR: 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile (CAS 372152-86-8) is a chemical compound with molecular formula C24H15ClN2OS2 and molecular weight 446.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(4-chlorophenyl)-2-phenacylsulfanyl-4-thiophen-2-ylpyridine-3-carbonitrile
Also Known As: 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile, 6-(4-chlorophenyl)-2-phenacylsulfanyl-4-thiophen-2-yl-pyridine-3-carbonitrile, 6-(4-chlorophenyl)-2-phenacylsulfanyl-4-thiophen-2-ylpyridine-3-carbonitrile, 6-(4-chlorophenyl)-2-[(2-oxo-2-phenylethyl)sulfanyl]-4-(thiophen-2-yl)pyridine-3-carbonitrile
| Molecular Formula | C24H15ClN2OS2 |
|---|---|
| Molecular Weight | 446.03 g/mol |
| LogP | 6.97718 |
| Topological Polar Surface Area | 53.75 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 446.03143 |
| Heavy Atoms | 30 |
| Complexity | 1214.8081 |
Chemical Identifiers
| CAS Number | 372152-86-8 |
|---|---|
| SMILES | C1=CC=C(C=C1)C(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)Cl)C4=CC=CS4)C#N |
Product Overview
6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile (CAS 372152-86-8), with molecular formula C24H15ClN2OS2 and molecular weight 446.03 g/mol. IUPAC: 6-(4-chlorophenyl)-2-phenacylsulfanyl-4-thiophen-2-ylpyridine-3-carbonitrile.
Chemical Property Profile of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile
Property Insights of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile
The XLogP value of 6.97718 indicates that 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.75 Ų, 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile?
The CAS number of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile is 372152-86-8.
What is the molecular formula of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile?
The molecular formula of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile is C24H15ClN2OS2.
What is the molecular weight of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile?
The molecular weight of 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile is 446.03 g/mol.
Where can I buy 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile?
You can request a quote for 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile?
Yes, KEHONG BIO provides custom synthesis services for 6-(4-chlorophenyl)-2-((2-oxo-2-phenylethyl)thio)-4-(thiophen-2-yl)nicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.