2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one
TL;DR: 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 372152-51-7) is a chemical compound with molecular formula C22H19FN2O3 and molecular weight 378.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-1,2-dihydroquinazolin-4-one
Also Known As: BAS 06731038, 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one, 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-1,2-dihydroquinazolin-4-one
| Molecular Formula | C22H19FN2O3 |
|---|---|
| Molecular Weight | 378.14 g/mol |
| LogP | 4.7011 |
| Topological Polar Surface Area | 61.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 378.13797 |
| Heavy Atoms | 28 |
| Complexity | 1037.7954 |
Chemical Identifiers
| CAS Number | 372152-51-7 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4F)O |
Product Overview
2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 372152-51-7), with molecular formula C22H19FN2O3 and molecular weight 378.14 g/mol. IUPAC: 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-1,2-dihydroquinazolin-4-one.
Chemical Property Profile of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one
Property Insights of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one
The XLogP value of 4.7011 indicates that 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one. Following Lipinski's Rule of Five, 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
The CAS number of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is 372152-51-7.
What is the molecular formula of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
The molecular formula of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is C22H19FN2O3.
What is the molecular weight of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
The molecular weight of 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is 378.14 g/mol.
Where can I buy 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
You can request a quote for 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(3-ethoxy-4-hydroxyphenyl)-3-(2-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.