1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid
TL;DR: 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid (CAS 372107-08-9) is a chemical compound with molecular formula C14H10N2O2S and molecular weight 270.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-phenyl-3-thiophen-2-ylpyrazole-4-carboxylic acid
Also Known As: 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid, 1-phenyl-3-thiophen-2-ylpyrazole-4-carboxylic acid, 1-Phenyl-3-thiophen-2-yl-1H-pyrazole-4-carboxylic acid, 1-phenyl-3-(2-thienyl)pyrazole-4-carboxylic acid, 1-phenyl-3-thien-2-yl-1H-pyrazole-4-carboxylic acid
| Molecular Formula | C14H10N2O2S |
|---|---|
| Molecular Weight | 270.05 g/mol |
| LogP | 3.299 |
| Topological Polar Surface Area | 55.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 270.0463 |
| Heavy Atoms | 19 |
| Complexity | 702.39343 |
Chemical Identifiers
| CAS Number | 372107-08-9 |
|---|---|
| SMILES | C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=CS3)C(=O)O |
Product Overview
1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid (CAS 372107-08-9), with molecular formula C14H10N2O2S and molecular weight 270.05 g/mol. IUPAC: 1-phenyl-3-thiophen-2-ylpyrazole-4-carboxylic acid.
Chemical Property Profile of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid
Property Insights of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid
The XLogP value of 3.299 indicates that 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.12 Ų, 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid?
The CAS number of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid is 372107-08-9.
What is the molecular formula of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid?
The molecular formula of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid is C14H10N2O2S.
What is the molecular weight of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid?
The molecular weight of 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid is 270.05 g/mol.
Where can I buy 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid?
You can request a quote for 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 1-phenyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.