2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one
TL;DR: 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 372083-92-6) is a chemical compound with molecular formula C29H24ClFN2O3 and molecular weight 502.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[(2-chlorophenyl)methoxy]-3-ethoxyphenyl]-3-(4-fluorophenyl)-1,2-dihydroquinazolin-4-one
Also Known As: 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one, 2-[4-[(2-chlorophenyl)methoxy]-3-ethoxy-phenyl]-3-(4-fluorophenyl)-1,2-dihydroquinazolin-4-one, 2-[4-[(2-chlorophenyl)methoxy]-3-ethoxyphenyl]-3-(4-fluorophenyl)-1,2-dihydroquinazolin-4-one, 2-{4-[(2-chlorobenzyl)oxy]-3-ethoxyphenyl}-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one, 2-{4-[(2-chlorophenyl)methoxy]-3-ethoxyphenyl}-3-(4-fluorophenyl)-1,2,3-trihyd roquinazolin-4-one
| Molecular Formula | C29H24ClFN2O3 |
|---|---|
| Molecular Weight | 502.15 g/mol |
| LogP | 7.2279 |
| Topological Polar Surface Area | 50.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 502.14594 |
| Heavy Atoms | 36 |
| Complexity | 1393.6703 |
Chemical Identifiers
| CAS Number | 372083-92-6 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)C2NC3=CC=CC=C3C(=O)N2C4=CC=C(C=C4)F)OCC5=CC=CC=C5Cl |
Product Overview
2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 372083-92-6), with molecular formula C29H24ClFN2O3 and molecular weight 502.15 g/mol. IUPAC: 2-[4-[(2-chlorophenyl)methoxy]-3-ethoxyphenyl]-3-(4-fluorophenyl)-1,2-dihydroquinazolin-4-one.
Chemical Property Profile of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one
Property Insights of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one
The XLogP value of 7.2279 indicates that 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.8 Ų, 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
The CAS number of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is 372083-92-6.
What is the molecular formula of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
The molecular formula of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is C29H24ClFN2O3.
What is the molecular weight of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
The molecular weight of 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one is 502.15 g/mol.
Where can I buy 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
You can request a quote for 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-((2-chlorobenzyl)oxy)-3-ethoxyphenyl)-3-(4-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.