(E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile
TL;DR: (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile (CAS 371948-07-1) is a chemical compound with molecular formula C21H10Cl2N2O2S and molecular weight 423.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-[4-(6-chloro-2-oxochromen-3-yl)-1,3-thiazol-2-yl]-3-(2-chlorophenyl)prop-2-enenitrile
Also Known As: (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile, 2-[4-(6-chloro-2-oxo-chromen-3-yl)-1,3-thiazol-2-yl]-3-(2-chlorophenyl)prop-2-enenitrile, (E)-2-[4-(6-chloro-2-oxochromen-3-yl)-1,3-thiazol-2-yl]-3-(2-chlorophenyl)prop-2-enenitrile
| Molecular Formula | C21H10Cl2N2O2S |
|---|---|
| Molecular Weight | 423.98 g/mol |
| LogP | 6.28748 |
| Topological Polar Surface Area | 66.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 423.984 |
| Heavy Atoms | 28 |
| Complexity | 1332.236 |
Chemical Identifiers
| CAS Number | 371948-07-1 |
|---|---|
| SMILES | C1=CC=C(C(=C1)/C=C(\C#N)/C2=NC(=CS2)C3=CC4=C(C=CC(=C4)Cl)OC3=O)Cl |
Product Overview
(E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile (CAS 371948-07-1), with molecular formula C21H10Cl2N2O2S and molecular weight 423.98 g/mol. IUPAC: (E)-2-[4-(6-chloro-2-oxochromen-3-yl)-1,3-thiazol-2-yl]-3-(2-chlorophenyl)prop-2-enenitrile.
Chemical Property Profile of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile
Property Insights of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile
The XLogP value of 6.28748 indicates that (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.89 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile. Following Lipinski's Rule of Five, (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile?
The CAS number of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile is 371948-07-1.
What is the molecular formula of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile?
The molecular formula of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile is C21H10Cl2N2O2S.
What is the molecular weight of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile?
The molecular weight of (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile is 423.98 g/mol.
Where can I buy (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile?
You can request a quote for (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-(6-chloro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)-3-(2-chlorophenyl)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.