4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile structure

4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile

TL;DR: 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile (CAS 371780-30-2) is a chemical compound with molecular formula C27H22N2O4S2 and molecular weight 502.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(3,4-dimethoxyphenyl)-2-[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl-6-thiophen-2-ylpyridine-3-carbonitrile

Also Known As: 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile, 4-(3,4-dimethoxyphenyl)-2-[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl-6-thiophen-2-ylpyridine-3-carbonitrile, 4-(3,4-dimethoxyphenyl)-2-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-6-(thiophen-2-yl)pyridine-3-carbonitrile

CAS: 371780-30-2
Molecular Formula C27H22N2O4S2
Molecular Weight 502.10 g/mol
LogP 6.34958
Topological Polar Surface Area 81.44 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 9
Exact Mass 502.1021
Heavy Atoms 35
Complexity 1377.8093

Chemical Identifiers

CAS Number 371780-30-2
SMILES COC1=CC=C(C=C1)C(=O)CSC2=C(C(=CC(=N2)C3=CC=CS3)C4=CC(=C(C=C4)OC)OC)C#N

Product Overview

4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile (CAS 371780-30-2), with molecular formula C27H22N2O4S2 and molecular weight 502.10 g/mol. IUPAC: 4-(3,4-dimethoxyphenyl)-2-[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl-6-thiophen-2-ylpyridine-3-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile

XLogP
6.34958
TPSA (Topological Polar Surface Area)
81.44
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
9
Heavy Atoms
35
Complexity
1377.8093
Exact Mass
502.1021
Monoisotopic Mass
502.1021
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile

The XLogP value of 6.34958 indicates that 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.44 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile. Following Lipinski's Rule of Five, 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile?

The CAS number of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile is 371780-30-2.

What is the molecular formula of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile?

The molecular formula of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile is C27H22N2O4S2.

What is the molecular weight of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile?

The molecular weight of 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile is 502.10 g/mol.

Where can I buy 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile?

You can request a quote for 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile?

Yes, KEHONG BIO provides custom synthesis services for 4-(3,4-dimethoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-6-(thiophen-2-yl)nicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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