Pyroglutamylhistidine
TL;DR: Pyroglutamylhistidine (CAS 37154-79-3) is a chemical compound with molecular formula C11H14N4O4 and molecular weight 266.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-3-(4H-imidazol-4-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoic acid
Also Known As: Pglu-his, Pyroglutamylhistidine, LHRH, L-Pyroglutamyl histidine, L-Histidine,5-oxo-L-prolyl-
| Molecular Formula | C11H14N4O4 |
|---|---|
| Molecular Weight | 266.10 g/mol |
| LogP | -1.7 |
| Topological Polar Surface Area | 120.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 266.1015 |
| Heavy Atoms | 19 |
| Complexity | 460.0 |
Chemical Identifiers
| CAS Number | 37154-79-3 |
|---|---|
| SMILES | C1CC(=O)N[C@@H]1C(=O)N[C@@H](CC2C=NC=N2)C(=O)O |
| InChIKey | DDQCRHMAPMBAFL-ALKRTJFJSA-N |
Product Overview
Pyroglutamylhistidine (CAS 37154-79-3), with molecular formula C11H14N4O4 and molecular weight 266.10 g/mol. IUPAC: (2S)-3-(4H-imidazol-4-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoic acid.
Chemical Property Profile of Pyroglutamylhistidine
Property Insights of Pyroglutamylhistidine
The XLogP value of -1.7 indicates that Pyroglutamylhistidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 120.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Pyroglutamylhistidine. Following Lipinski's Rule of Five, Pyroglutamylhistidine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamylhistidine?
The CAS number of Pyroglutamylhistidine is 37154-79-3.
What is the molecular formula of Pyroglutamylhistidine?
The molecular formula of Pyroglutamylhistidine is C11H14N4O4.
What is the molecular weight of Pyroglutamylhistidine?
The molecular weight of Pyroglutamylhistidine is 266.10 g/mol.
Where can I buy Pyroglutamylhistidine?
You can request a quote for Pyroglutamylhistidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamylhistidine?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamylhistidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.